CRCGN015_MCF10A_48H:L24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description carbon-tetrachloride 10.92 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN015_MCF10A_48H:L24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 4.9734
CDH18 cadherin 18, type 2 2.98525
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.6887
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.6694
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.56372
CCNA1 cyclin A1 2.49295
SPPL2A signal peptide peptidase like 2A 2.45855
PREB prolactin regulatory element binding 2.36625
RRAGB Ras-related GTP binding B 2.28005
CUL1 cullin 1 2.15515
ACTC1 actin, alpha, cardiac muscle 1 2.0936
ACSS3 acyl-CoA synthetase short-chain family member 3 2.0625
GPKOW G patch domain and KOW motifs 2.0565
CHEK2 checkpoint kinase 2 2.03253

decreased expression

Symbol Name Standardized Value
KRT7 keratin 7, type II -6.04295
GOLT1B golgi transport 1B -5.0
LDHB lactate dehydrogenase B -4.54897
PLS1 plastin 1 -4.20035
RECQL RecQ helicase-like -4.16535
PARP2 poly (ADP-ribose) polymerase 2 -3.59527
KRT14 keratin 14, type I -3.0632
ANXA3 annexin A3 -3.05695
ERGIC2 ERGIC and golgi 2 -2.87605
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -2.86595
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -2.85485
SRFBP1 serum response factor binding protein 1 -2.82995
RCE1 Ras converting CAAX endopeptidase 1 -2.6927
IFT46 intraflagellar transport 46 -2.5559
ZNF212 zinc finger protein 212 -2.51465
INTS13 integrator complex subunit 13 -2.30145
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -2.30105
ERCC1 excision repair cross-complementation group 1 -2.20458
VIM vimentin -2.15195
MED21 mediator complex subunit 21 -2.1276
BBLN bublin coiled coil protein -2.05937
EI24 etoposide induced 2.4 -2.03045
RARS1 arginyl-tRNA synthetase 1 -2.0201
PLEKHA5 pleckstrin homology domain containing, family A member 5 -2.0168
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 -2.00445