CRCGN015_MCF10A_48H:M01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitromethane 99.8 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN015_MCF10A_48H:M01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 4.64968
TOMM34 translocase of outer mitochondrial membrane 34 3.03262
ILK integrin-linked kinase 2.69948
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 2.36953
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.28578
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 2.21657
SECTM1 secreted and transmembrane 1 2.18206
RTF2 replication termination factor 2 2.11287

decreased expression

Symbol Name Standardized Value
MT2A metallothionein 2A -4.34258
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -3.84044
EIF5 eukaryotic translation initiation factor 5 -3.77498
S100A8 S100 calcium binding protein A8 -3.17145
RPIA ribose 5-phosphate isomerase A -3.01519
MELK maternal embryonic leucine zipper kinase -2.93333
TM9SF3 transmembrane 9 superfamily member 3 -2.89676
PRKCQ protein kinase C, theta -2.33086
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -2.27359
KRT14 keratin 14, type I -2.20668
MYO5A myosin VA (heavy chain 12, myoxin) -2.17618
CREG1 cellular repressor of E1A-stimulated genes 1 -2.17277
GLOD4 glyoxalase domain containing 4 -2.13263
TBC1D31 TBC1 domain family, member 31 -2.12497
KIF21B kinesin family member 21B -2.12171
FKBP11 FK506 binding protein 11, 19 kDa -2.11054
CSRP2 cysteine and glycine-rich protein 2 -2.08509
YJU2B YJU2 splicing factor homolog B -2.01792
EFL1 elongation factor like GTPase 1 -2.01105