CRCGN015_MCF10A_48H:M05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethyl hydrogen phosphite 33.43 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN015_MCF10A_48H:M05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TIAM1 T-cell lymphoma invasion and metastasis 1 3.67896
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.74683
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.71401
SIRT3 sirtuin 3 2.5488
RSF1 remodeling and spacing factor 1 2.46384
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.40432
MCOLN3 mucolipin 3 2.27355
MREG melanoregulin 2.19311
MOXD1 monooxygenase, DBH-like 1 2.163
LGALS14 lectin, galactoside-binding, soluble, 14 2.12752
GLI3 GLI family zinc finger 3 2.10114
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.06617
DEAF1 DEAF1 transcription factor 2.04442
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.04354
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 2.02227
LAMP3 lysosomal-associated membrane protein 3 2.01987

decreased expression

Symbol Name Standardized Value
CCNH cyclin H -6.77071
COG7 component of oligomeric golgi complex 7 -5.00367
IGFBP7 insulin-like growth factor binding protein 7 -4.49743
VIM vimentin -3.23458
MT2A metallothionein 2A -3.1362
TM9SF3 transmembrane 9 superfamily member 3 -3.06017
ADI1 acireductone dioxygenase 1 -2.43275
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 -2.42712
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -2.3624
BCAS1 breast carcinoma amplified sequence 1 -2.19781
BTBD1 BTB (POZ) domain containing 1 -2.12228
PCCB propionyl CoA carboxylase, beta polypeptide -2.10649
ZFYVE16 zinc finger, FYVE domain containing 16 -2.03887
TRPV4 transient receptor potential cation channel, subfamily V, member 4 -2.0331
BCAS2 breast carcinoma amplified sequence 2 -2.02421
HSPA1A heat shock 70kDa protein 1A -2.01674
KRT14 keratin 14, type I -2.00512