CRCGN015_MCF10A_48H:M09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description norethynodrel 11.14 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN015_MCF10A_48H:M09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MOK MOK protein kinase 3.60933
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 3.28945
ANO10 anoctamin 10 3.02061
GFPT1 glutamine--fructose-6-phosphate transaminase 1 2.8116
FHL2 four and a half LIM domains 2 2.77487
ILK integrin-linked kinase 2.71736
SCRN1 secernin 1 2.486
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.23808
VGLL4 vestigial-like family member 4 2.15752
TXNRD1 thioredoxin reductase 1 2.12811
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.0079

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -3.85331
CAB39 calcium binding protein 39 -3.71944
ENOPH1 enolase-phosphatase 1 -3.16403
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.04311
POLR1G RNA polymerase I subunit G -2.18307
TCEAL4 transcription elongation factor A (SII)-like 4 -2.07635
COPS4 COP9 signalosome subunit 4 -2.07357
PLS1 plastin 1 -2.04713
STK25 serine/threonine kinase 25 -2.03045