CRCGN015_MCF10A_48H:M10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methylhydrazine sulfate 100.8 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN015_MCF10A_48H:M10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZNF589 zinc finger protein 589 3.38982
PRKCH protein kinase C, eta 3.38032
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.9904
SNX11 sorting nexin 11 2.85523
IFI44L interferon-induced protein 44-like 2.11983
PELI2 pellino E3 ubiquitin protein ligase family member 2 2.11416
TRIM22 tripartite motif containing 22 2.10007
PLA2G2D phospholipase A2, group IID 2.00347

decreased expression

Symbol Name Standardized Value
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.30598
S100A8 S100 calcium binding protein A8 -3.91411
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.42998
MT2A metallothionein 2A -3.01637
KRT14 keratin 14, type I -2.0535