CRCGN015_MCF10A_48H:M11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methylhydrazine sulfate 33.6 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN015_MCF10A_48H:M11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COQ8A coenzyme Q8A 6.13386
METRN meteorin, glial cell differentiation regulator 3.89661
KDM5A lysine (K)-specific demethylase 5A 2.90114
MAMLD1 mastermind-like domain containing 1 2.48347
RAB31 RAB31, member RAS oncogene family 2.35724
NUCB2 nucleobindin 2 2.07155

decreased expression

Symbol Name Standardized Value
VIM vimentin -3.2841
CSRP2 cysteine and glycine-rich protein 2 -3.07968
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -2.46013
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 -2.35172
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.31691
FBXO21 F-box protein 21 -2.299
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.26739
MARK1 MAP/microtubule affinity-regulating kinase 1 -2.17077
CD58 CD58 molecule -2.10247
IGSF3 immunoglobulin superfamily, member 3 -2.05558