CRCGN015_MCF10A_48H:M13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dichloroethane 96.8 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_MCF10A_48H:M13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STAP2 signal transducing adaptor family member 2 4.05015
PRKCH protein kinase C, eta 3.85986
ZNF318 zinc finger protein 318 3.77994
CIAO3 cytosolic iron-sulfur assembly component 3 3.34844
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.74371
SCAND1 SCAN domain containing 1 2.7122
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.66868
KLHL36 kelch-like family member 36 2.43206
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 2.42034
CLCN5 chloride channel, voltage-sensitive 5 2.36561
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 2.12033
RCN3 reticulocalbin 3, EF-hand calcium binding domain 2.00588

decreased expression

Symbol Name Standardized Value
PLK2 polo-like kinase 2 -4.60798
IGFBP7 insulin-like growth factor binding protein 7 -3.66431
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.51281
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.20169
VIM vimentin -3.17321
NCK1 NCK adaptor protein 1 -2.97771
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.7199
A2M alpha-2-macroglobulin -2.12317
COG2 component of oligomeric golgi complex 2 -2.02641