CRCGN015_MCF10A_48H:M21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mestranol 10.87 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

28 genes differentially expressed following the CRCGN015_MCF10A_48H:M21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NOSIP nitric oxide synthase interacting protein 3.30602
WIF1 WNT inhibitory factor 1 2.7216
TXNL4B thioredoxin-like 4B 2.65412
USP6NL USP6 N-terminal like 2.64789
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.57228
BMP4 bone morphogenetic protein 4 2.5266
HKDC1 hexokinase domain containing 1 2.41009
MCUB mitochondrial calcium uniporter dominant negative subunit beta 2.20833
PRR7 proline rich 7 (synaptic) 2.17902
ECI1 enoyl-CoA delta isomerase 1 2.17271
PECR peroxisomal trans-2-enoyl-CoA reductase 2.14709
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.10243
TWNK twinkle mtDNA helicase 2.1023
USP11 ubiquitin specific peptidase 11 2.0975
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 2.0922

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -5.61398
RNF167 ring finger protein 167 -4.93112
UFM1 ubiquitin-fold modifier 1 -4.8068
ATG4A autophagy related 4A, cysteine peptidase -2.58723
DUSP14 dual specificity phosphatase 14 -2.26278
COPZ2 coatomer protein complex, subunit zeta 2 -2.16011
GSTA4 glutathione S-transferase alpha 4 -2.12808
TMEM164 transmembrane protein 164 -2.05829
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 -2.04689
MRPL17 mitochondrial ribosomal protein L17 -2.04681
MSMO1 methylsterol monooxygenase 1 -2.04142
MRPS31 mitochondrial ribosomal protein S31 -2.03012
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 -2.02193