CRCGN015_MCF10A_48H:M24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-nitropyrene 11.33 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

424 genes differentially expressed following the CRCGN015_MCF10A_48H:M24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 5.6777
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 4.25685
SESN1 sestrin 1 4.08225
RGS2 regulator of G-protein signaling 2 3.87515
MYL9 myosin, light chain 9, regulatory 3.8643
CSRNP2 cysteine-serine-rich nuclear protein 2 3.7463
FHL2 four and a half LIM domains 2 3.62655
FAT1 FAT atypical cadherin 1 3.50935
INPP1 inositol polyphosphate-1-phosphatase 3.4878
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.47665
AMOTL2 angiomotin like 2 3.41425
TCEAL4 transcription elongation factor A (SII)-like 4 3.3426
MOK MOK protein kinase 3.2125
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 3.16895
CALCOCO1 calcium binding and coiled-coil domain 1 3.1527
KLHL21 kelch-like family member 21 3.1361
PNKP polynucleotide kinase 3'-phosphatase 3.12335
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.10721
LAMA5 laminin, alpha 5 3.04545
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.96929
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.95835
ACTA2 actin, alpha 2, smooth muscle, aorta 2.95015
MYLK myosin light chain kinase 2.92455
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.80275
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.7929
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.783
TUFT1 tuftelin 1 2.7647
RAP1GAP2 RAP1 GTPase activating protein 2 2.76185
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.74775
FDXR ferredoxin reductase 2.74635
TRIB1 tribbles pseudokinase 1 2.72125
BECN1 beclin 1, autophagy related 2.69353
EPS8L2 EPS8-like 2 2.6642
SYNRG synergin, gamma 2.66407
EGF epidermal growth factor 2.60885
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 2.57195
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.5543
IFI6 interferon, alpha-inducible protein 6 2.54615
GADD45A growth arrest and DNA-damage-inducible, alpha 2.5267
MBD1 methyl-CpG binding domain protein 1 2.50765
EXOSC4 exosome component 4 2.5059
COL9A2 collagen, type IX, alpha 2 2.50185
PXDC1 PX domain containing 1 2.5002
OLFML2A olfactomedin-like 2A 2.4915
GLT8D2 glycosyltransferase 8 domain containing 2 2.48915
IL36A interleukin 36, alpha 2.48715
DDB2 damage-specific DNA binding protein 2, 48kDa 2.4687
TMEM40 transmembrane protein 40 2.46785
STAT2 signal transducer and activator of transcription 2, 113kDa 2.45755
EMC7 ER membrane protein complex subunit 7 2.43735
GTF2B general transcription factor IIB 2.42765
TERF2IP telomeric repeat binding factor 2, interacting protein 2.4124
ARMCX1 armadillo repeat containing, X-linked 1 2.4093
PDLIM2 PDZ and LIM domain 2 (mystique) 2.4022
SCRIB scribbled planar cell polarity protein 2.40105
TIGAR TP53 induced glycolysis regulatory phosphatase 2.3984
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.3976
ZBP1 Z-DNA binding protein 1 2.3966
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 2.39558
ZBED2 zinc finger, BED-type containing 2 2.3827
SEC31B SEC31 homolog B (S. cerevisiae) 2.3814
SKIC2 SKI2 subunit of superkiller complex 2.3684
TRIM22 tripartite motif containing 22 2.36575
ARMCX3 armadillo repeat containing, X-linked 3 2.357
CLDN16 claudin 16 2.3567
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.35665
CNN1 calponin 1, basic, smooth muscle 2.35095
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 2.34304
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.33815
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.33715
IP6K2 inositol hexakisphosphate kinase 2 2.3336
TASL TLR adaptor interacting with endolysosomal SLC15A4 2.33315
NGRN neugrin, neurite outgrowth associated 2.3306
ABAT 4-aminobutyrate aminotransferase 2.32823
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2.31135
PRSS8 protease, serine, 8 2.3102
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 2.30925
FRMD4B FERM domain containing 4B 2.30755
CDK5RAP1 CDK5 regulatory subunit associated protein 1 2.30525
WLS wntless Wnt ligand secretion mediator 2.3034
DUSP7 dual specificity phosphatase 7 2.29487
DKK3 dickkopf WNT signaling pathway inhibitor 3 2.29005
DACH1 dachshund family transcription factor 1 2.28757
CCDC86 coiled-coil domain containing 86 2.2828
RTP4 receptor (chemosensory) transporter protein 4 2.2799
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 2.27685
WASHC5 WASH complex subunit 5 2.2763
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.27535
ZNF212 zinc finger protein 212 2.2698
TMEM59 transmembrane protein 59 2.2687
GIMAP4 GTPase, IMAP family member 4 2.2687
ZC3H12A zinc finger CCCH-type containing 12A 2.26855
BBS1 Bardet-Biedl syndrome 1 2.25965
SAA2 serum amyloid A2 2.2553
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.25425
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 2.25345
PGPEP1 pyroglutamyl-peptidase I 2.25205
WBP1L WW domain binding protein 1-like 2.24365
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 2.2355
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.2347
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 2.23105
ARSA arylsulfatase A 2.22865
SSH3 slingshot protein phosphatase 3 2.22853
CPEB3 cytoplasmic polyadenylation element binding protein 3 2.22685
GDF15 growth differentiation factor 15 2.22245
SUGCT succinyl-CoA:glutarate-CoA transferase 2.21465
CRHBP corticotropin releasing hormone binding protein 2.2108
FBXL12 F-box and leucine-rich repeat protein 12 2.2088
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 2.20055
WDR45B WD repeat domain 45B 2.19945
ZNF506 zinc finger protein 506 2.1991
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.19865
ACTG2 actin, gamma 2, smooth muscle, enteric 2.19365
SCAND1 SCAN domain containing 1 2.19105
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 2.18905
EHD3 EH-domain containing 3 2.18885
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.18312
MAIP1 matrix AAA peptidase interacting protein 1 2.1815
TMPRSS5 transmembrane protease, serine 5 2.16815
CHMP5 charged multivesicular body protein 5 2.1675
SPTBN5 spectrin, beta, non-erythrocytic 5 2.1661
TRAFD1 TRAF-type zinc finger domain containing 1 2.16535
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.151
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.14835
ZNF562 zinc finger protein 562 2.14495
GDI1 GDP dissociation inhibitor 1 2.13625
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.13558
TCEAL1 transcription elongation factor A (SII)-like 1 2.13345
OPLAH 5-oxoprolinase (ATP-hydrolysing) 2.1321
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 2.1318
ARHGAP29 Rho GTPase activating protein 29 2.1245
KIFC3 kinesin family member C3 2.12305
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.12225
CHKB choline kinase beta 2.1119
KDM6B lysine (K)-specific demethylase 6B 2.1114
AMIGO2 adhesion molecule with Ig-like domain 2 2.1067
TRIM5 tripartite motif containing 5 2.09905
ARHGAP4 Rho GTPase activating protein 4 2.09695
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.0948
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.0934
SHARPIN SHANK-associated RH domain interactor 2.09275
MINK1 misshapen-like kinase 1 2.09104
CTSK cathepsin K 2.08915
TMEM265 transmembrane protein 265 2.08698
TBKBP1 TBK1 binding protein 1 2.0848
RANBP10 RAN binding protein 10 2.0777
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.0746
ZNF211 zinc finger protein 211 2.0742
NISCH nischarin 2.07035
DEGS1 delta(4)-desaturase, sphingolipid 1 2.06988
THBS2 thrombospondin 2 2.0651
PLXNB2 plexin B2 2.06105
ATG2A autophagy related 2A 2.0609
BLCAP bladder cancer associated protein 2.06055
GAL3ST4 galactose-3-O-sulfotransferase 4 2.05915
GOLGA8N golgin A8 family, member N 2.0574
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 2.05574
PYCARD PYD and CARD domain containing 2.0542
CAVIN1 caveolae associated protein 1 2.0516
TPCN1 two pore segment channel 1 2.0511
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 2.0496
PWWP3A PWWP domain containing 3A, DNA repair factor 2.0491
SIN3B SIN3 transcription regulator family member B 2.04677
KIAA1614 KIAA1614 2.0426
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.04045
PCDHA10 protocadherin alpha 10 2.04025
PPP1R3C protein phosphatase 1, regulatory subunit 3C 2.0393
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 2.0383
MN1 meningioma (disrupted in balanced translocation) 1 2.03765
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.0333
ZNHIT6 zinc finger, HIT-type containing 6 2.031
ZIM3 zinc finger, imprinted 3 2.0307
BCL2L2 BCL2-like 2 2.02515
ARHGAP8 Rho GTPase activating protein 8 2.02432
RAB11FIP5 RAB11 family interacting protein 5 (class I) 2.0233
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.02163
KATNIP katanin interacting protein 2.01775
GSTM3 glutathione S-transferase mu 3 (brain) 2.0164
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.01375
MSI1 musashi RNA-binding protein 1 2.01275
SIRT2 sirtuin 2 2.0107
MTCH1 mitochondrial carrier 1 2.00975
OPTN optineurin 2.00933

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -5.42725
CDK1 cyclin-dependent kinase 1 -4.67463
CCNB2 cyclin B2 -4.55765
CCNA2 cyclin A2 -4.22067
GINS2 GINS complex subunit 2 (Psf2 homolog) -4.193
KIF14 kinesin family member 14 -4.16655
TTK TTK protein kinase -4.05045
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.01555
KIF18A kinesin family member 18A -3.93275
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.88525
CDC45 cell division cycle 45 -3.8073
HJURP Holliday junction recognition protein -3.7617
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.73535
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.69735
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -3.6807
TOP2A topoisomerase (DNA) II alpha 170kDa -3.64095
CDKN3 cyclin-dependent kinase inhibitor 3 -3.63545
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.63475
DBF4 DBF4 zinc finger -3.6136
ELOVL6 ELOVL fatty acid elongase 6 -3.56647
KIF15 kinesin family member 15 -3.54305
ERCC6L excision repair cross-complementation group 6-like -3.53085
EXO1 exonuclease 1 -3.5281
SPC25 SPC25, NDC80 kinetochore complex component -3.525
DCK deoxycytidine kinase -3.50135
MELK maternal embryonic leucine zipper kinase -3.47635
CHEK1 checkpoint kinase 1 -3.47093
PARP1 poly (ADP-ribose) polymerase 1 -3.46345
PLK1 polo-like kinase 1 -3.4453
NCAPH non-SMC condensin I complex, subunit H -3.4074
CKS2 CDC28 protein kinase regulatory subunit 2 -3.40205
ATAD2 ATPase family, AAA domain containing 2 -3.395
RRM2 ribonucleotide reductase M2 -3.37913
FBXO5 F-box protein 5 -3.37185
MCM5 minichromosome maintenance complex component 5 -3.35322
MKI67 marker of proliferation Ki-67 -3.35301
KIF11 kinesin family member 11 -3.34105
MCM6 minichromosome maintenance complex component 6 -3.3309
NUSAP1 nucleolar and spindle associated protein 1 -3.29783
H2AZ1 H2A.Z variant histone 1 -3.24135
CDC25B cell division cycle 25B -3.1697
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.1646
FIRRM FIGNL1 interacting regulator of recombination and mitosis -3.16445
UBE2C ubiquitin-conjugating enzyme E2C -3.14115
HMGB2 high mobility group box 2 -3.12225
HPRT1 hypoxanthine phosphoribosyltransferase 1 -3.12095
S100A8 S100 calcium binding protein A8 -3.12085
RACGAP1 Rac GTPase activating protein 1 -3.11885
TPX2 TPX2, microtubule-associated -3.08775
NCAPG2 non-SMC condensin II complex, subunit G2 -3.0786
ASF1B anti-silencing function 1B histone chaperone -3.0734
ANAPC15 anaphase promoting complex subunit 15 -3.05195
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.044
SSBP2 single-stranded DNA binding protein 2 -3.0397
CDCA8 cell division cycle associated 8 -3.02995
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -3.00255
CDCA3 cell division cycle associated 3 -3.00165
KIF20A kinesin family member 20A -2.9906
RMI1 RecQ mediated genome instability 1 -2.9866
CENPM centromere protein M -2.98185
KIF23 kinesin family member 23 -2.9774
CENPA centromere protein A -2.97555
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.96065
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.94985
CDC25C cell division cycle 25C -2.92745
RBMX RNA binding motif protein, X-linked -2.9188
FANCC Fanconi anemia, complementation group C -2.90465
CDCA4 cell division cycle associated 4 -2.8974
VRK1 vaccinia related kinase 1 -2.8894
OIP5 Opa interacting protein 5 -2.88775
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.88155
RFC2 replication factor C (activator 1) 2, 40kDa -2.87855
CENPN centromere protein N -2.8707
NEK2 NIMA-related kinase 2 -2.86035
TRAF1 TNF receptor-associated factor 1 -2.8597
TRIP13 thyroid hormone receptor interactor 13 -2.8441
KIF4A kinesin family member 4A -2.83095
MAPKAP1 mitogen-activated protein kinase associated protein 1 -2.8279
SKA1 spindle and kinetochore associated complex subunit 1 -2.7977
CCNB1 cyclin B1 -2.75815
DDIT4 DNA-damage-inducible transcript 4 -2.75675
DHFR dihydrofolate reductase -2.75583
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.7499
MCM7 minichromosome maintenance complex component 7 -2.73422
PBK PDZ binding kinase -2.7312
PRC1 protein regulator of cytokinesis 1 -2.73075
TMEM38B transmembrane protein 38B -2.71065
PLK4 polo-like kinase 4 -2.7099
PTTG1 pituitary tumor-transforming 1 -2.7079
GLRX5 glutaredoxin 5 -2.68975
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.68705
CENPU centromere protein U -2.67215
BIRC5 baculoviral IAP repeat containing 5 -2.6698
CENPI centromere protein I -2.66445
ANAPC10 anaphase promoting complex subunit 10 -2.6602
MCM10 minichromosome maintenance complex component 10 -2.6513
ALG9 ALG9, alpha-1,2-mannosyltransferase -2.6332
MCM4 minichromosome maintenance complex component 4 -2.62893
SNRPA small nuclear ribonucleoprotein polypeptide A -2.6147
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.5977
IARS1 isoleucyl-tRNA synthetase 1 -2.5968
GPHN gephyrin -2.59265
TMEM267 transmembrane protein 267 -2.59065
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) -2.5824
TACC3 transforming, acidic coiled-coil containing protein 3 -2.58195
PCNA proliferating cell nuclear antigen -2.54755
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.53943
STMN1 stathmin 1 -2.5374
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.5359
PARPBP PARP1 binding protein -2.53055
ANO10 anoctamin 10 -2.5043
RFC3 replication factor C (activator 1) 3, 38kDa -2.5012
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.50085
CDK4 cyclin-dependent kinase 4 -2.4957
RPS5 ribosomal protein S5 -2.4938
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.49378
ATF5 activating transcription factor 5 -2.49293
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.48565
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.48078
PCLAF PCNA clamp associated factor -2.4773
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.4683
LMNB1 lamin B1 -2.4586
CDC6 cell division cycle 6 -2.45522
TSPAN3 tetraspanin 3 -2.4534
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.4396
KIAA0586 KIAA0586 -2.4323
DEPDC1 DEP domain containing 1 -2.41225
PALS2 protein associated with LIN7 2, MAGUK p55 family member -2.4064
PARN poly(A)-specific ribonuclease -2.40505
ECT2 epithelial cell transforming 2 -2.4039
CBR3 carbonyl reductase 3 -2.4033
SNX5 sorting nexin 5 -2.399
NDC80 NDC80 kinetochore complex component -2.39755
MMP9 matrix metallopeptidase 9 -2.3958
CADPS2 Ca++-dependent secretion activator 2 -2.3953
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -2.38365
YEATS4 YEATS domain containing 4 -2.3722
POLK polymerase (DNA directed) kappa -2.3621
CENPE centromere protein E, 312kDa -2.35855
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.3546
CENPS-CORT CENPS-CORT readthrough -2.34965
FANCI Fanconi anemia, complementation group I -2.34805
GTF2A2 general transcription factor IIA, 2, 12kDa -2.34495
NTAQ1 N-terminal glutamine amidase 1 -2.33645
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -2.3358
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.32265
CEP76 centrosomal protein 76kDa -2.3066
CDT1 chromatin licensing and DNA replication factor 1 -2.30455
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -2.2877
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.28285
TIPIN TIMELESS interacting protein -2.27895
TLCD3A TLC domain containing 3A -2.2753
ZWINT ZW10 interacting kinetochore protein -2.26685
BLMH bleomycin hydrolase -2.26575
RXYLT1 ribitol xylosyltransferase 1 -2.25867
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.25777
ENOPH1 enolase-phosphatase 1 -2.25025
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.24965
USP39 ubiquitin specific peptidase 39 -2.2457
KIFC1 kinesin family member C1 -2.24555
MCM3 minichromosome maintenance complex component 3 -2.24145
CD58 CD58 molecule -2.23692
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 -2.23585
ZSCAN5A zinc finger and SCAN domain containing 5A -2.2355
PSRC1 proline/serine-rich coiled-coil 1 -2.22765
AFG3L2 AFG3-like AAA ATPase 2 -2.22745
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.2255
RPIA ribose 5-phosphate isomerase A -2.21775
FEN1 flap structure-specific endonuclease 1 -2.21758
SEC13 SEC13 homolog (S. cerevisiae) -2.2117
ZDHHC6 zinc finger, DHHC-type containing 6 -2.2115
NMD3 NMD3 ribosome export adaptor -2.2107
RFC4 replication factor C (activator 1) 4, 37kDa -2.21055
CD320 CD320 molecule -2.20575
FOXM1 forkhead box M1 -2.20505
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.2013
GTSE1 G-2 and S-phase expressed 1 -2.19785
SLC31A1 solute carrier family 31 (copper transporter), member 1 -2.1919
SLC25A40 solute carrier family 25, member 40 -2.1915
SP8 Sp8 transcription factor -2.19043
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.19015
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.1816
MIS18A MIS18 kinetochore protein A -2.1763
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.17595
HSPA8 heat shock 70kDa protein 8 -2.17503
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -2.1659
DSCC1 DNA replication and sister chromatid cohesion 1 -2.16555
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -2.16535
NUP85 nucleoporin 85kDa -2.1628
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -2.16065
ELOVL2 ELOVL fatty acid elongase 2 -2.16008
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.15698
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.15695
RPL18 ribosomal protein L18 -2.1512
ORC6 origin recognition complex, subunit 6 -2.149
SPAG5 sperm associated antigen 5 -2.14815
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.1466
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.13835
DCPS decapping enzyme, scavenger -2.1303
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -2.1266
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.12457
CCL19 chemokine (C-C motif) ligand 19 -2.1179
PRKCB protein kinase C, beta -2.1054
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.10495
RBBP7 retinoblastoma binding protein 7 -2.10355
CGREF1 cell growth regulator with EF-hand domain 1 -2.1013
ARSJ arylsulfatase family, member J -2.0984
MCUB mitochondrial calcium uniporter dominant negative subunit beta -2.096
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -2.09592
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.08505
BLM Bloom syndrome, RecQ helicase-like -2.0842
ZWILCH zwilch kinetochore protein -2.08275
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.07915
IPO5 importin 5 -2.07771
CENPF centromere protein F, 350/400kDa -2.07063
VTA1 vesicle (multivesicular body) trafficking 1 -2.06975
RPA3 replication protein A3, 14kDa -2.06485
CPAP centrosome assembly and centriole elongation protein -2.06035
SAE1 SUMO1 activating enzyme subunit 1 -2.05895
GABPA GA binding protein transcription factor, alpha subunit 60kDa -2.05495
TRIM28 tripartite motif containing 28 -2.05345
TUBA1B tubulin, alpha 1b -2.03525
NCAPG non-SMC condensin I complex, subunit G -2.03332
SPIB Spi-B transcription factor (Spi-1/PU.1 related) -2.0323
CTSE cathepsin E -2.03035
CYREN cell cycle regulator of NHEJ -2.02955
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -2.0293
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -2.02795
HEMK2 HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine -2.0278
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.0267
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.02163
SHCBP1 SHC SH2-domain binding protein 1 -2.0216
BRCA1 breast cancer 1, early onset -2.0186
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin -2.01795
HMGB3 high mobility group box 3 -2.013
SLC25A46 solute carrier family 25, member 46 -2.01245
SIVA1 SIVA1, apoptosis-inducing factor -2.0118
GNA12 guanine nucleotide binding protein (G protein) alpha 12 -2.0113
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -2.006
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.004
TXLNG taxilin gamma -2.00335