CRCGN015_MCF10A_48H:N01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyleneimine 104.79 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_MCF10A_48H:N01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYLK myosin light chain kinase 4.13893
STK10 serine/threonine kinase 10 4.05301
CXCL2 chemokine (C-X-C motif) ligand 2 3.58899
SNX11 sorting nexin 11 3.12541
CCNA1 cyclin A1 2.45966
TSPAN6 tetraspanin 6 2.27175
SPON1 spondin 1, extracellular matrix protein 2.16461
GADD45A growth arrest and DNA-damage-inducible, alpha 2.05307
CBX1 chromobox homolog 1 2.00832

decreased expression

Symbol Name Standardized Value
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -3.58912
MT2A metallothionein 2A -3.10062
TM9SF3 transmembrane 9 superfamily member 3 -2.58177
PLK2 polo-like kinase 2 -2.45262
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -2.38013
FAM168B family with sequence similarity 168, member B -2.13311
LDHB lactate dehydrogenase B -2.1009
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -2.07229