CRCGN015_MCF10A_48H:N02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyleneimine 34.93 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN015_MCF10A_48H:N02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HLA-DRA major histocompatibility complex, class II, DR alpha 2.7398
TXNL4B thioredoxin-like 4B 2.53635
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 2.46725
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.31525
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 2.30893
HOXA11 homeobox A11 2.23546
MICU1 mitochondrial calcium uptake 1 2.21885
PRR15L proline rich 15-like 2.21452
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.21164
EFNA4 ephrin-A4 2.1556
ZNF184 zinc finger protein 184 2.08744
PID1 phosphotyrosine interaction domain containing 1 2.0835
ELAC2 elaC ribonuclease Z 2 2.08216
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 2.05302
TTC33 tetratricopeptide repeat domain 33 2.04682
DCTPP1 dCTP pyrophosphatase 1 2.04575
GAR1 GAR1 ribonucleoprotein 2.04143
ZNF32 zinc finger protein 32 2.03822
SNX15 sorting nexin 15 2.0321
SMIM40 small integral membrane protein 40 2.02332
OXR1 oxidation resistance 1 2.01995
SBDS Shwachman-Bodian-Diamond syndrome 2.00333

decreased expression

Symbol Name Standardized Value
MELK maternal embryonic leucine zipper kinase -3.41345
ANXA3 annexin A3 -2.58873
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -2.42666
VAT1 vesicle amine transport 1 -2.30662
TCTA T-cell leukemia translocation altered -2.2759
FSTL1 follistatin-like 1 -2.20811
VCP valosin containing protein -2.14609
PSIP1 PC4 and SFRS1 interacting protein 1 -2.09615
PCNA proliferating cell nuclear antigen -2.03239
MAP4 microtubule-associated protein 4 -2.03034