CRCGN015_MCF10A_48H:N03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyleneimine 11.64 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_MCF10A_48H:N03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STK10 serine/threonine kinase 10 5.23792
ABHD4 abhydrolase domain containing 4 4.99574
SMIM40 small integral membrane protein 40 4.18959
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 3.43367
SIRT3 sirtuin 3 3.32019
ADAT1 adenosine deaminase, tRNA-specific 1 3.14572
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.95171
ZNF354A zinc finger protein 354A 2.69725
TMEM186 transmembrane protein 186 2.66685
BFAR bifunctional apoptosis regulator 2.53554
THUMPD1 THUMP domain containing 1 2.44608
CADPS2 Ca++-dependent secretion activator 2 2.29958
ZNF165 zinc finger protein 165 2.20297
POGLUT1 protein O-glucosyltransferase 1 2.14478
AMZ2 archaelysin family metallopeptidase 2 2.12979
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.11705
GNA12 guanine nucleotide binding protein (G protein) alpha 12 2.10774
REPS1 RALBP1 associated Eps domain containing 1 2.10281
BOLA1 bolA family member 1 2.086
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 2.07741
AIDA axin interactor, dorsalization associated 2.04331
CHN1 chimerin 1 2.03612

decreased expression

Symbol Name Standardized Value
DERA deoxyribose-phosphate aldolase (putative) -3.65598
S100A8 S100 calcium binding protein A8 -2.66684
PLK2 polo-like kinase 2 -2.28657
MT2A metallothionein 2A -2.27501
CRLF1 cytokine receptor-like factor 1 -2.1919
TM9SF3 transmembrane 9 superfamily member 3 -2.12332
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -2.11336