CRCGN015_MCF10A_48H:N04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description naphthalene 99.3 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN015_MCF10A_48H:N04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCDC92 coiled-coil domain containing 92 4.82213
TOMM34 translocase of outer mitochondrial membrane 34 4.75142
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.84004
HBA1 hemoglobin, alpha 1 3.75142
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.31713
MMP24-AS1-EDEM2 MMP24-AS1-EDEM2 readthrough 2.08896
PRSS2 protease, serine, 2 (trypsin 2) 2.07444
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 2.04445
PRKX protein kinase, X-linked 2.04258
KIFAP3 kinesin-associated protein 3 2.0405
MFSD6 major facilitator superfamily domain containing 6 2.0383
LCN2 lipocalin 2 2.01764
NUAK2 NUAK family, SNF1-like kinase, 2 2.01592
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.01217
PI3 peptidase inhibitor 3, skin-derived 2.00572

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -5.36919
HSPA1A heat shock 70kDa protein 1A -5.06437
ARPP19 cAMP-regulated phosphoprotein, 19kDa -3.89385
PLS1 plastin 1 -2.75857
MAPK6 mitogen-activated protein kinase 6 -2.45595
CSRP2 cysteine and glycine-rich protein 2 -2.41024
PHLDA2 pleckstrin homology-like domain, family A, member 2 -2.29769
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -2.29276
ANXA3 annexin A3 -2.27966
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.24157
OARD1 O-acyl-ADP-ribose deacylase 1 -2.20913
PENK proenkephalin -2.17758
ZMYM2 zinc finger, MYM-type 2 -2.16831
MCM3 minichromosome maintenance complex component 3 -2.1423
ZNF266 zinc finger protein 266 -2.13174
MYO5C myosin VC -2.11494
GRN granulin -2.08107
MYO5A myosin VA (heavy chain 12, myoxin) -2.0589
ABR active BCR-related -2.00293