CRCGN015_MCF10A_48H:N09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isobutyl nitrite 10.7 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_MCF10A_48H:N09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 4.36143
BAX BCL2-associated X protein 4.24301
NT5DC2 5'-nucleotidase domain containing 2 3.48884
HOXA10-HOXA9 HOXA10-HOXA9 readthrough 2.43386
LMNB1 lamin B1 2.38421
HIRA histone cell cycle regulator 2.32077
HBA1 hemoglobin, alpha 1 2.30513
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 2.29759
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 2.19802
ARID4A AT rich interactive domain 4A (RBP1-like) 2.11887
CCDC85B coiled-coil domain containing 85B 2.10126
SBNO1 strawberry notch homolog 1 (Drosophila) 2.09325

decreased expression

Symbol Name Standardized Value
MT2A metallothionein 2A -6.4531
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.43672
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.37453
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -4.00566
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.68428
TJP1 tight junction protein 1 -2.62584
ATOX1 antioxidant 1 copper chaperone -2.46857
NECAP2 NECAP endocytosis associated 2 -2.33504
CTSD cathepsin D -2.31952
RAB38 RAB38, member RAS oncogene family -2.24265
LOC124907782 dual specificity protein phosphatase 22 -2.22549
TMEM164 transmembrane protein 164 -2.20151
RNF187 ring finger protein 187 -2.10632
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) -2.04841
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -2.04594
ATG4A autophagy related 4A, cysteine peptidase -2.02264
HIRIP3 HIRA interacting protein 3 -2.01727
ZNF16 zinc finger protein 16 -2.00866
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.00468