CRCGN015_MCF10A_48H:N10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tetranitromethane 101.3 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_MCF10A_48H:N10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FKBP14 FK506 binding protein 14, 22 kDa 4.7406
ANO10 anoctamin 10 3.49088
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.15461
CHEK2 checkpoint kinase 2 2.54184
GRAMD1B GRAM domain containing 1B 2.38792
SLC16A4 solute carrier family 16, member 4 2.27701
SH2D4A SH2 domain containing 4A 2.10579
SMTN smoothelin 2.08407
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.02147
ANKLE2 ankyrin repeat and LEM domain containing 2 2.00798

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -3.35169
MT2A metallothionein 2A -3.05382
MT1X metallothionein 1X -2.79732
KRT14 keratin 14, type I -2.45774
CSRP2 cysteine and glycine-rich protein 2 -2.34431
LOC124905743 low affinity immunoglobulin gamma Fc region receptor III-B -2.13769
PLK2 polo-like kinase 2 -2.10783
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -2.08221
PODXL podocalyxin-like -2.03733