| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | cobalt sulfate heptahydrate 11.14 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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78 genes differentially expressed following the CRCGN015_MCF10A_48H:N15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HBA1 | hemoglobin, alpha 1 | 4.7236 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.94332 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 2.78287 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.74486 |
| JUN | jun proto-oncogene | 2.73282 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.56882 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 2.52295 |
| DHDDS | dehydrodolichyl diphosphate synthase | 2.45901 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.42086 |
| ARHGAP15 | Rho GTPase activating protein 15 | 2.36405 |
| KLF13 | Kruppel-like factor 13 | 2.31739 |
| WDR76 | WD repeat domain 76 | 2.2993 |
| SFMBT1 | Scm-like with four mbt domains 1 | 2.25475 |
| CELF2 | CUGBP, Elav-like family member 2 | 2.24802 |
| SCAF11 | SR-related CTD-associated factor 11 | 2.22367 |
| OXR1 | oxidation resistance 1 | 2.21468 |
| STEAP4 | STEAP family member 4 | 2.20583 |
| SOSTDC1 | sclerostin domain containing 1 | 2.18696 |
| GFI1 | growth factor independent 1 transcription repressor | 2.18163 |
| IL12RB2 | interleukin 12 receptor, beta 2 | 2.1715 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 2.1633 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 2.15057 |
| NUTF2 | nuclear transport factor 2 | 2.12608 |
| GPSM2 | G-protein signaling modulator 2 | 2.10432 |
| TGFBR3 | transforming growth factor, beta receptor III | 2.10098 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 2.08392 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 2.08086 |
| RIOX1 | ribosomal oxygenase 1 | 2.06195 |
| ZNF22 | zinc finger protein 22 | 2.05689 |
| CNN3 | calponin 3, acidic | 2.04612 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 2.04498 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 2.04279 |
| ALDOC | aldolase C, fructose-bisphosphate | 2.04105 |
| RRAGA | Ras-related GTP binding A | 2.03471 |
| QARS1 | glutaminyl-tRNA synthetase 1 | 2.02247 |
| LRRN3 | leucine rich repeat neuronal 3 | 2.01752 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 2.00407 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 2.001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPDC1 | neural proliferation, differentiation and control, 1 | -5.3118 |
| SLC25A46 | solute carrier family 25, member 46 | -5.28066 |
| NCK1 | NCK adaptor protein 1 | -5.26709 |
| COG7 | component of oligomeric golgi complex 7 | -3.89095 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.6675 |
| ISOC1 | isochorismatase domain containing 1 | -3.3409 |
| MRPL34 | mitochondrial ribosomal protein L34 | -3.33801 |
| ATG3 | autophagy related 3 | -2.77594 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | -2.54297 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase | -2.5344 |
| PZP | pregnancy-zone protein | -2.43791 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 | -2.42743 |
| MELK | maternal embryonic leucine zipper kinase | -2.4271 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | -2.41273 |
| PLK2 | polo-like kinase 2 | -2.39985 |
| TSPAN13 | tetraspanin 13 | -2.39235 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.3395 |
| AEN | apoptosis enhancing nuclease | -2.31321 |
| ASB6 | ankyrin repeat and SOCS box containing 6 | -2.30511 |
| HOXD10 | homeobox D10 | -2.28969 |
| COTL1 | coactosin-like F-actin binding protein 1 | -2.26807 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -2.25329 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -2.25197 |
| ANXA10 | annexin A10 | -2.2277 |
| STRA6 | stimulated by retinoic acid 6 | -2.21079 |
| ZGPAT | zinc finger, CCCH-type with G patch domain | -2.18907 |
| CTSL | cathepsin L | -2.15612 |
| SIRAL2 | SIR2 antiphage like 2 | -2.14247 |
| SAP30L | SAP30-like | -2.11437 |
| POMT1 | protein-O-mannosyltransferase 1 | -2.0836 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa | -2.06054 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | -2.05641 |
| IFT20 | intraflagellar transport 20 | -2.05422 |
| IL36G | interleukin 36, gamma | -2.04825 |
| EMC6 | ER membrane protein complex subunit 6 | -2.04559 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | -2.04086 |
| DUSP5 | dual specificity phosphatase 5 | -2.03421 |
| ZDHHC11B | zinc finger, DHHC-type containing 11B | -2.02705 |
| CCNL1 | cyclin L1 | -2.0157 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.01414 |
