CRCGN015_MCF10A_48H:N17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-epoxybutane 32.43 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

11 genes differentially expressed following the CRCGN015_MCF10A_48H:N17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NOSIP nitric oxide synthase interacting protein 3.72368
USP6NL USP6 N-terminal like 2.55051
ABHD4 abhydrolase domain containing 4 2.43697
PECR peroxisomal trans-2-enoyl-CoA reductase 2.3044
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 2.10822
PRKX protein kinase, X-linked 2.01698

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.67122
TM9SF3 transmembrane 9 superfamily member 3 -2.99506
PDLIM1 PDZ and LIM domain 1 -2.37025
GRN granulin -2.08796
S100A4 S100 calcium binding protein A4 -2.0784