CRCGN015_MCF10A_48H:N19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN015_MCF10A_48H:N19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 5.3835
HBA1 hemoglobin, alpha 1 4.13349
ZW10 zw10 kinetochore protein 3.31542
LPL lipoprotein lipase 2.6942
ADIPOQ adiponectin, C1Q and collagen domain containing 2.49278
RBP4 retinol binding protein 4, plasma 2.47316
DHDDS dehydrodolichyl diphosphate synthase 2.32503
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 2.29265
LEP leptin 2.16386
PLIN1 perilipin 1 2.13356
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 2.09192
GPC3 glypican 3 2.00393
SLCO2A1 solute carrier organic anion transporter family, member 2A1 2.00333

decreased expression

Symbol Name Standardized Value
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.57881
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -4.50544
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -4.10013
CIDEB cell death-inducing DFFA-like effector b -2.64677
PDLIM1 PDZ and LIM domain 1 -2.51227
PTPRK protein tyrosine phosphatase, receptor type, K -2.45167
S100A8 S100 calcium binding protein A8 -2.34667
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 -2.24297
CYTH3 cytohesin 3 -2.16803
MELK maternal embryonic leucine zipper kinase -2.16454
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.16091
AKR1D1 aldo-keto reductase family 1, member D1 -2.07037
CD72 CD72 molecule -2.00804