CRCGN015_MCF10A_48H:N23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phenylephrine 33.93 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN015_MCF10A_48H:N23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DLK1 delta-like 1 homolog (Drosophila) 5.3885
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 3.59463
SIRT3 sirtuin 3 3.35195
WDR7 WD repeat domain 7 3.14329
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.88531
KLHL21 kelch-like family member 21 2.30906
PECR peroxisomal trans-2-enoyl-CoA reductase 2.27755
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.26509
TRIM13 tripartite motif containing 13 2.23628
SRR serine racemase 2.21592
FBXL12 F-box and leucine-rich repeat protein 12 2.20203
TLK2 tousled-like kinase 2 2.19859
SGSM2 small G protein signaling modulator 2 2.18156
RTN2 reticulon 2 2.15086
SOCS2 suppressor of cytokine signaling 2 2.14198
CAMK1 calcium/calmodulin-dependent protein kinase I 2.11107
ETFB electron-transfer-flavoprotein, beta polypeptide 2.08319
NHLRC2 NHL repeat containing 2 2.07084
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.04374

decreased expression

Symbol Name Standardized Value
EIF5 eukaryotic translation initiation factor 5 -3.80744
FASTKD5 FAST kinase domains 5 -3.35524
VIM vimentin -3.32716
VAT1 vesicle amine transport 1 -2.86814
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -2.3376
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -2.3
CLCN3 chloride channel, voltage-sensitive 3 -2.13435
CALM1 calmodulin 1 (phosphorylase kinase, delta) -2.12876
NFIL3 nuclear factor, interleukin 3 regulated -2.12007
WSB2 WD repeat and SOCS box containing 2 -2.10408
TRIM38 tripartite motif containing 38 -2.09249
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.0888
CASC3 cancer susceptibility candidate 3 -2.0851
EGLN1 egl-9 family hypoxia-inducible factor 1 -2.03754
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -2.00455