CRCGN015_MCF10A_48H:N24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phenylephrine 11.31 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

46 genes differentially expressed following the CRCGN015_MCF10A_48H:N24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SMIM40 small integral membrane protein 40 4.1335
IGHMBP2 immunoglobulin mu binding protein 2 3.03197
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.57587
FRS3 fibroblast growth factor receptor substrate 3 2.40227
NT5DC2 5'-nucleotidase domain containing 2 2.38476
KLHL21 kelch-like family member 21 2.27573
WDR46 WD repeat domain 46 2.25958
GNG3 guanine nucleotide binding protein (G protein), gamma 3 2.22693
NTSR1 neurotensin receptor 1 (high affinity) 2.20692
ANGPTL2 angiopoietin-like 2 2.19649
TRPV4 transient receptor potential cation channel, subfamily V, member 4 2.19069
NT5DC3 5'-nucleotidase domain containing 3 2.10663
PTGDR prostaglandin D2 receptor (DP) 2.0998
NDOR1 NADPH dependent diflavin oxidoreductase 1 2.08785
CMA1 chymase 1, mast cell 2.07444
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 2.02184
GPC5 glypican 5 2.00539
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.00474

decreased expression

Symbol Name Standardized Value
TBP TATA box binding protein -4.7454
GOLT1B golgi transport 1B -4.51455
RECQL RecQ helicase-like -4.23439
MED21 mediator complex subunit 21 -2.88156
KRT14 keratin 14, type I -2.84805
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -2.78642
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.71342
INTS13 integrator complex subunit 13 -2.58911
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -2.4494
ISOC1 isochorismatase domain containing 1 -2.35475
IFI30 interferon, gamma-inducible protein 30 -2.30483
KRT7 keratin 7, type II -2.30162
MCM9 minichromosome maintenance complex component 9 -2.2629
IFT20 intraflagellar transport 20 -2.23255
ERGIC2 ERGIC and golgi 2 -2.22799
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.21034
ZNF302 zinc finger protein 302 -2.17548
CRTC3 CREB regulated transcription coactivator 3 -2.13874
SDHAF1 succinate dehydrogenase complex assembly factor 1 -2.13317
ZNF384 zinc finger protein 384 -2.13127
RMDN1 regulator of microtubule dynamics 1 -2.13107
ETNK1 ethanolamine kinase 1 -2.10691
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -2.08598
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -2.06684
ZNF672 zinc finger protein 672 -2.06495
TMED1 transmembrane emp24 protein transport domain containing 1 -2.0264
LETMD1 LETM1 domain containing 1 -2.00906
GET1 guided entry of tail-anchored proteins factor 1 -2.0015