CRCGN015_MCF10A_48H:O01 Gene Set
Genes
41 genes differentially expressed following the CRCGN015_MCF10A_48H:O01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUCB2
|
nucleobindin 2
|
7.47464
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
4.16598
|
|
S100A4
|
S100 calcium binding protein A4
|
3.86713
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.80867
|
|
ELAC2
|
elaC ribonuclease Z 2
|
2.78388
|
|
PYCR1
|
pyrroline-5-carboxylate reductase 1
|
2.59167
|
|
RUVBL2
|
RuvB-like AAA ATPase 2
|
2.21867
|
|
HBA1
|
hemoglobin, alpha 1
|
2.18513
|
|
RLIG1
|
RNA 5'-phosphate and 3'-OH ligase 1
|
2.17634
|
|
MRPS22
|
mitochondrial ribosomal protein S22
|
2.14881
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.099
|
|
USP6NL
|
USP6 N-terminal like
|
2.07106
|
|
MYOD1
|
myogenic differentiation 1
|
2.05425
|
|
PSME1
|
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
|
2.04557
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
2.0455
|
|
TMCO1
|
transmembrane and coiled-coil domains 1
|
2.0151
|
|
GYG1
|
glycogenin 1
|
2.00601
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
-4.54214
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-4.49112
|
|
FOXJ3
|
forkhead box J3
|
-3.47411
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
-3.24934
|
|
OAT
|
ornithine aminotransferase
|
-2.86358
|
|
CRKL
|
v-crk avian sarcoma virus CT10 oncogene homolog-like
|
-2.31418
|
|
NLRP2
|
NLR family, pyrin domain containing 2
|
-2.2775
|
|
LDHB
|
lactate dehydrogenase B
|
-2.25745
|
|
COL13A1
|
collagen, type XIII, alpha 1
|
-2.23132
|
|
TRIM49D2
|
tripartite motif containing 49D2
|
-2.18849
|
|
LRRC19
|
leucine rich repeat containing 19
|
-2.16502
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
-2.13438
|
|
PRAME
|
preferentially expressed antigen in melanoma
|
-2.12836
|
|
HAAO
|
3-hydroxyanthranilate 3,4-dioxygenase
|
-2.11754
|
|
ZKSCAN8
|
zinc finger with KRAB and SCAN domains 8
|
-2.11536
|
|
CHAMP1
|
chromosome alignment maintaining phosphoprotein 1
|
-2.10471
|
|
STARD3
|
StAR-related lipid transfer (START) domain containing 3
|
-2.10109
|
|
H2AB2
|
H2A.B variant histone 2
|
-2.09163
|
|
HMG20B
|
high mobility group 20B
|
-2.08642
|
|
LGSN
|
lengsin, lens protein with glutamine synthetase domain
|
-2.06306
|
|
CHIT1
|
chitinase 1 (chitotriosidase)
|
-2.02516
|
|
LAMP3
|
lysosomal-associated membrane protein 3
|
-2.0216
|
|
PRDM13
|
PR domain containing 13
|
-2.01577
|
|
SMG9
|
SMG9 nonsense mediated mRNA decay factor
|
-2.00481
|