CRCGN015_MCF10A_48H:O05 Gene Set
Genes
31 genes differentially expressed following the CRCGN015_MCF10A_48H:O05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.4277
|
|
WIF1
|
WNT inhibitory factor 1
|
3.0534
|
|
KLHL21
|
kelch-like family member 21
|
3.02375
|
|
PKN1
|
protein kinase N1
|
2.72018
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
2.7064
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
2.461
|
|
STK10
|
serine/threonine kinase 10
|
2.26375
|
|
KCTD5
|
potassium channel tetramerization domain containing 5
|
2.21025
|
|
NARS2
|
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
|
2.21005
|
|
RSF1
|
remodeling and spacing factor 1
|
2.15935
|
|
MRPL19
|
mitochondrial ribosomal protein L19
|
2.1477
|
|
SPG21
|
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
|
2.11
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.04185
|
|
TOPORS
|
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
|
2.0209
|
|
APPL2
|
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
|
2.0078
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
-5.0519
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-4.5339
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.3595
|
|
AKR7A3
|
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
|
-4.15688
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-3.6899
|
|
MT2A
|
metallothionein 2A
|
-3.60075
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.5076
|
|
CAB39
|
calcium binding protein 39
|
-3.3962
|
|
SNTA1
|
syntrophin, alpha 1
|
-2.81335
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-2.76923
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-2.2872
|
|
LOC124908558
|
X antigen family member 1-like
|
-2.1588
|
|
ATG4A
|
autophagy related 4A, cysteine peptidase
|
-2.0894
|
|
APLNR
|
apelin receptor
|
-2.07085
|
|
SSX3
|
synovial sarcoma, X breakpoint 3
|
-2.07055
|
|
VIM
|
vimentin
|
-2.0191
|
