CRCGN015_MCF10A_48H:O09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description indometacin 11.07 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN015_MCF10A_48H:O09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HBA1 hemoglobin, alpha 1 4.40043
FBXL12 F-box and leucine-rich repeat protein 12 4.09512
WASF3 WAS protein family, member 3 3.58924
GET1 guided entry of tail-anchored proteins factor 1 2.46063
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.17355
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.08124

decreased expression

Symbol Name Standardized Value
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.68812
CCDC86 coiled-coil domain containing 86 -3.09403
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -2.57006
KIAA0319L KIAA0319-like -2.50212
GLTP glycolipid transfer protein -2.47792
SOWAHC sosondowah ankyrin repeat domain family member C -2.16159
STAT1 signal transducer and activator of transcription 1, 91kDa -2.14126
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -2.02182
UNKL unkempt family zinc finger-like -2.01924
PRPF4 pre-mRNA processing factor 4 -2.0103