CRCGN015_MCF10A_48H:O15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description catechol 10.99 um perturbation at 48 h in MCF10A (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

87 genes differentially expressed following the CRCGN015_MCF10A_48H:O15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PRKCQ protein kinase C, theta 5.62065
ADO 2-aminoethanethiol (cysteamine) dioxygenase 5.47938
GRWD1 glutamate-rich WD repeat containing 1 4.84712
ABHD6 abhydrolase domain containing 6 4.12179
ZNF26 zinc finger protein 26 2.72235
TYRP1 tyrosinase-related protein 1 2.51974
DNASE1L3 deoxyribonuclease I-like 3 2.51561
PFKL phosphofructokinase, liver 2.47598
CLIP2 CAP-GLY domain containing linker protein 2 2.43603
NRBF2 nuclear receptor binding factor 2 2.42093
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 2.38533
ZBTB11 zinc finger and BTB domain containing 11 2.35317
PRR5L proline rich 5 like 2.34153
EXD2 exonuclease 3'-5' domain containing 2 2.33666
RCOR1 REST corepressor 1 2.33386
F2R coagulation factor II (thrombin) receptor 2.32426
GATA2 GATA binding protein 2 2.29271
TP53TG5 TP53 target 5 2.29102
UBE2G2 ubiquitin-conjugating enzyme E2G 2 2.28458
TMEM267 transmembrane protein 267 2.27955
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 2.26457
TYR tyrosinase 2.20153
HTD2 hydroxyacyl-thioester dehydratase type 2 2.1722
MSL2 male-specific lethal 2 homolog (Drosophila) 2.15901
WDR33 WD repeat domain 33 2.14605
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 2.14327
USP6 ubiquitin specific peptidase 6 2.13952
PAXBP1 PAX3 and PAX7 binding protein 1 2.13447
CEP57 centrosomal protein 57kDa 2.12169
GYS1 glycogen synthase 1 (muscle) 2.12042
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 2.12031
CD99 CD99 molecule 2.11182
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 2.11084
MTMR6 myotubularin related protein 6 2.0963
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 2.08932
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.08546
POLR2M polymerase (RNA) II (DNA directed) polypeptide M 2.07755
TSPAN8 tetraspanin 8 2.0724
GATD3 glutamine amidotransferase class 1 domain containing 3 2.06603
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.05746
DET1 de-etiolated homolog 1 (Arabidopsis) 2.05628
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 2.04948
TRAPPC10 trafficking protein particle complex 10 2.03831
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 2.01727
ZBTB10 zinc finger and BTB domain containing 10 2.01466
FLG filaggrin 2.01004
RAB17 RAB17, member RAS oncogene family 2.00391

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -8.71757
MT2A metallothionein 2A -3.3486
TM9SF3 transmembrane 9 superfamily member 3 -2.96851
S100A6 S100 calcium binding protein A6 -2.85761
VSIG4 V-set and immunoglobulin domain containing 4 -2.64182
RBM34 RNA binding motif protein 34 -2.57968
MT1X metallothionein 1X -2.46984
LMO3 LIM domain only 3 (rhombotin-like 2) -2.45627
MGP matrix Gla protein -2.4489
IFRD2 interferon-related developmental regulator 2 -2.41731
REXO2 RNA exonuclease 2 -2.41042
COPS5 COP9 signalosome subunit 5 -2.38546
TRPS1 trichorhinophalangeal syndrome I -2.37504
GBP2 guanylate binding protein 2, interferon-inducible -2.32807
ELF5 E74-like factor 5 (ets domain transcription factor) -2.31598
NME3 NME/NM23 nucleoside diphosphate kinase 3 -2.31161
LPAR6 lysophosphatidic acid receptor 6 -2.30323
GRIA2 glutamate receptor, ionotropic, AMPA 2 -2.29021
ANTKMT adenine nucleotide translocase lysine methyltransferase -2.28891
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.27362
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -2.2466
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -2.19802
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -2.18492
DLX5 distal-less homeobox 5 -2.17632
ADAM9 ADAM metallopeptidase domain 9 -2.14951
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -2.14702
RND3 Rho family GTPase 3 -2.13653
SOD2 superoxide dismutase 2, mitochondrial -2.13522
TDP2 tyrosyl-DNA phosphodiesterase 2 -2.12962
TBCE tubulin folding cofactor E -2.1188
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -2.09701
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -2.06835
PALMD palmdelphin -2.05386
YIPF3 Yip1 domain family, member 3 -2.05369
TUBG2 tubulin, gamma 2 -2.05343
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -2.05016
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin -2.03885
TMED1 transmembrane emp24 protein transport domain containing 1 -2.01778
ACP2 acid phosphatase 2, lysosomal -2.00911
SIX3 SIX homeobox 3 -2.00805