| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | catechol 10.99 um perturbation at 48 h in MCF10A (Carcinogenome) |
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87 genes differentially expressed following the CRCGN015_MCF10A_48H:O15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKCQ | protein kinase C, theta | 5.62065 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 5.47938 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 4.84712 |
| ABHD6 | abhydrolase domain containing 6 | 4.12179 |
| ZNF26 | zinc finger protein 26 | 2.72235 |
| TYRP1 | tyrosinase-related protein 1 | 2.51974 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 2.51561 |
| PFKL | phosphofructokinase, liver | 2.47598 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 2.43603 |
| NRBF2 | nuclear receptor binding factor 2 | 2.42093 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 2.38533 |
| ZBTB11 | zinc finger and BTB domain containing 11 | 2.35317 |
| PRR5L | proline rich 5 like | 2.34153 |
| EXD2 | exonuclease 3'-5' domain containing 2 | 2.33666 |
| RCOR1 | REST corepressor 1 | 2.33386 |
| F2R | coagulation factor II (thrombin) receptor | 2.32426 |
| GATA2 | GATA binding protein 2 | 2.29271 |
| TP53TG5 | TP53 target 5 | 2.29102 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 2.28458 |
| TMEM267 | transmembrane protein 267 | 2.27955 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 2.26457 |
| TYR | tyrosinase | 2.20153 |
| HTD2 | hydroxyacyl-thioester dehydratase type 2 | 2.1722 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | 2.15901 |
| WDR33 | WD repeat domain 33 | 2.14605 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | 2.14327 |
| USP6 | ubiquitin specific peptidase 6 | 2.13952 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | 2.13447 |
| CEP57 | centrosomal protein 57kDa | 2.12169 |
| GYS1 | glycogen synthase 1 (muscle) | 2.12042 |
| GTF2E1 | general transcription factor IIE, polypeptide 1, alpha 56kDa | 2.12031 |
| CD99 | CD99 molecule | 2.11182 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | 2.11084 |
| MTMR6 | myotubularin related protein 6 | 2.0963 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 2.08932 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.08546 |
| POLR2M | polymerase (RNA) II (DNA directed) polypeptide M | 2.07755 |
| TSPAN8 | tetraspanin 8 | 2.0724 |
| GATD3 | glutamine amidotransferase class 1 domain containing 3 | 2.06603 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.05746 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) | 2.05628 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa | 2.04948 |
| TRAPPC10 | trafficking protein particle complex 10 | 2.03831 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 2.01727 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 2.01466 |
| FLG | filaggrin | 2.01004 |
| RAB17 | RAB17, member RAS oncogene family | 2.00391 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT14 | keratin 14, type I | -8.71757 |
| MT2A | metallothionein 2A | -3.3486 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.96851 |
| S100A6 | S100 calcium binding protein A6 | -2.85761 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -2.64182 |
| RBM34 | RNA binding motif protein 34 | -2.57968 |
| MT1X | metallothionein 1X | -2.46984 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -2.45627 |
| MGP | matrix Gla protein | -2.4489 |
| IFRD2 | interferon-related developmental regulator 2 | -2.41731 |
| REXO2 | RNA exonuclease 2 | -2.41042 |
| COPS5 | COP9 signalosome subunit 5 | -2.38546 |
| TRPS1 | trichorhinophalangeal syndrome I | -2.37504 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -2.32807 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -2.31598 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | -2.31161 |
| LPAR6 | lysophosphatidic acid receptor 6 | -2.30323 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -2.29021 |
| ANTKMT | adenine nucleotide translocase lysine methyltransferase | -2.28891 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -2.27362 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) | -2.2466 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -2.19802 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | -2.18492 |
| DLX5 | distal-less homeobox 5 | -2.17632 |
| ADAM9 | ADAM metallopeptidase domain 9 | -2.14951 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | -2.14702 |
| RND3 | Rho family GTPase 3 | -2.13653 |
| SOD2 | superoxide dismutase 2, mitochondrial | -2.13522 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | -2.12962 |
| TBCE | tubulin folding cofactor E | -2.1188 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -2.09701 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -2.06835 |
| PALMD | palmdelphin | -2.05386 |
| YIPF3 | Yip1 domain family, member 3 | -2.05369 |
| TUBG2 | tubulin, gamma 2 | -2.05343 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -2.05016 |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | -2.03885 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 | -2.01778 |
| ACP2 | acid phosphatase 2, lysosomal | -2.00911 |
| SIX3 | SIX homeobox 3 | -2.00805 |