CRCGN015_MCF10A_48H:O17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 5-nitroacenaphthene 32.8 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

28 genes differentially expressed following the CRCGN015_MCF10A_48H:O17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 5.33636
PDIA5 protein disulfide isomerase family A, member 5 3.2047
ZNF589 zinc finger protein 589 3.20237
SNX11 sorting nexin 11 3.08734
KLHL21 kelch-like family member 21 2.69604
PPARG peroxisome proliferator-activated receptor gamma 2.45876
CAPN5 calpain 5 2.44297
TLR6 toll-like receptor 6 2.40963
CBR3 carbonyl reductase 3 2.38463
PKN1 protein kinase N1 2.36397
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.26052
NPC1 Niemann-Pick disease, type C1 2.14174
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.07338
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.03252
PHF20L1 PHD finger protein 20-like 1 2.01416

decreased expression

Symbol Name Standardized Value
RPIA ribose 5-phosphate isomerase A -5.38693
DCK deoxycytidine kinase -4.97409
DUSP6 dual specificity phosphatase 6 -3.51045
KRT14 keratin 14, type I -3.4008
S100A8 S100 calcium binding protein A8 -3.3617
NUP85 nucleoporin 85kDa -3.31194
HEBP1 heme binding protein 1 -2.39832
MRPS7 mitochondrial ribosomal protein S7 -2.26404
MLF1 myeloid leukemia factor 1 -2.23526
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.14417
TMED1 transmembrane emp24 protein transport domain containing 1 -2.0979
MCM9 minichromosome maintenance complex component 9 -2.04437
CSRP2 cysteine and glycine-rich protein 2 -2.0197