CRCGN015_MCF10A_48H:O18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 5-nitroacenaphthene 10.93 um perturbation at 48 h in MCF10A (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

24 genes differentially expressed following the CRCGN015_MCF10A_48H:O18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 5.60582
PRKCQ protein kinase C, theta 4.78825
CIAO3 cytosolic iron-sulfur assembly component 3 4.74395
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 3.206
MCPH1 microcephalin 1 2.2878
S1PR4 sphingosine-1-phosphate receptor 4 2.285
ELAC2 elaC ribonuclease Z 2 2.28335
ANTKMT adenine nucleotide translocase lysine methyltransferase 2.28175
NRBF2 nuclear receptor binding factor 2 2.2727
PCM1 pericentriolar material 1 2.16865
GFI1 growth factor independent 1 transcription repressor 2.1404
ATP9B ATPase, class II, type 9B 2.1099
TTI2 TELO2 interacting protein 2 2.0954
MRPS15 mitochondrial ribosomal protein S15 2.02515

decreased expression

Symbol Name Standardized Value
PLK2 polo-like kinase 2 -5.0
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.9382
CHMP4B charged multivesicular body protein 4B -4.46718
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -4.07075
KRT7 keratin 7, type II -3.06975
CSRP2 cysteine and glycine-rich protein 2 -3.00148
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.8072
FAM131A family with sequence similarity 131, member A -2.27745
ATP11B ATPase, class VI, type 11B -2.16125
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -2.01945