CRCGN015_MCF10A_48H:O19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sulfallate 100.72 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

40 genes differentially expressed following the CRCGN015_MCF10A_48H:O19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SMIM40 small integral membrane protein 40 4.72883
HBA1 hemoglobin, alpha 1 3.52707
PDIA5 protein disulfide isomerase family A, member 5 2.97918
IGHMBP2 immunoglobulin mu binding protein 2 2.73136
FMR1 fragile X mental retardation 1 2.69238
RNF144A ring finger protein 144A 2.53622
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.42032
SLC75A1 solute carrier family 75 member 1 2.26166
GOLGA4 golgin A4 2.24861
MDC1 mediator of DNA-damage checkpoint 1 2.23848
RNPS1 RNA binding protein S1, serine-rich domain 2.23599
SLC35F2 solute carrier family 35, member F2 2.22634
PPT2 palmitoyl-protein thioesterase 2 2.10857
FKTN fukutin 2.0691
EMD emerin 2.05408
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.05389

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -4.27483
CAB39 calcium binding protein 39 -4.08079
HEATR1 HEAT repeat containing 1 -3.24411
MT2A metallothionein 2A -3.12976
STXBP2 syntaxin binding protein 2 -3.1021
VIM vimentin -3.07369
STAT1 signal transducer and activator of transcription 1, 91kDa -2.9759
EXT1 exostosin glycosyltransferase 1 -2.7049
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -2.42478
MT1X metallothionein 1X -2.36512
STEAP1 six transmembrane epithelial antigen of the prostate 1 -2.3118
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) -2.30976
CD37 CD37 molecule -2.23739
LDHB lactate dehydrogenase B -2.2264
CD52 CD52 molecule -2.20967
DMAC2L distal membrane arm assembly component 2 like -2.16672
HSPB1 heat shock 27kDa protein 1 -2.14639
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.11834
LOC124900388 uncharacterized LOC124900388 -2.11508
FCGRT Fc fragment of IgG, receptor, transporter, alpha -2.07472
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -2.06434
ZNF432 zinc finger protein 432 -2.04597
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -2.02005
TMEM160 transmembrane protein 160 -2.01858