CRCGN015_MCF10A_48H:O21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sulfallate 11.19 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

52 genes differentially expressed following the CRCGN015_MCF10A_48H:O21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HBA1 hemoglobin, alpha 1 4.24767
SNX11 sorting nexin 11 3.73692
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.41637
KDM5D lysine (K)-specific demethylase 5D 3.31822
TBXA2R thromboxane A2 receptor 2.8754
SLC75A1 solute carrier family 75 member 1 2.75418
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.50902
NUP62 nucleoporin 62kDa 2.48521
KLHL21 kelch-like family member 21 2.47843
CARD8 caspase recruitment domain family, member 8 2.23071
USP9Y ubiquitin specific peptidase 9, Y-linked 2.19138
GP1BA glycoprotein Ib (platelet), alpha polypeptide 2.1738
HOXA4 homeobox A4 2.14771
RNF4 ring finger protein 4 2.13971
DHDDS dehydrodolichyl diphosphate synthase 2.1325
ITGA7 integrin, alpha 7 2.10144
ZBTB16 zinc finger and BTB domain containing 16 2.07074
NHLRC2 NHL repeat containing 2 2.06069
BMPR1A bone morphogenetic protein receptor, type IA 2.05874
TENT5A terminal nucleotidyltransferase 5A 2.05328
AZU1 azurocidin 1 2.04344
KANK1 KN motif and ankyrin repeat domains 1 2.03113

decreased expression

Symbol Name Standardized Value
PLK2 polo-like kinase 2 -2.77073
KRT7 keratin 7, type II -2.76137
SMC1A structural maintenance of chromosomes 1A -2.51618
ACP5 acid phosphatase 5, tartrate resistant -2.49393
ZFYVE16 zinc finger, FYVE domain containing 16 -2.43086
CREG1 cellular repressor of E1A-stimulated genes 1 -2.30217
RAB15 RAB15, member RAS oncogene family -2.28967
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.26559
NDN necdin, melanoma antigen (MAGE) family member -2.25074
SH3GLB2 SH3-domain GRB2-like endophilin B2 -2.24456
PDCD1 programmed cell death 1 -2.23753
FGGY FGGY carbohydrate kinase domain containing -2.19751
PNPLA4 patatin-like phospholipase domain containing 4 -2.18369
RALGDS ral guanine nucleotide dissociation stimulator -2.17941
COL5A1 collagen, type V, alpha 1 -2.17053
AP4M1 adaptor-related protein complex 4, mu 1 subunit -2.14743
NLRP4 NLR family, pyrin domain containing 4 -2.14673
UBA1 ubiquitin-like modifier activating enzyme 1 -2.07948
MNX1 motor neuron and pancreas homeobox 1 -2.07838
CDK16 cyclin-dependent kinase 16 -2.07653
COMP cartilage oligomeric matrix protein -2.07044
KDM5C lysine (K)-specific demethylase 5C -2.07026
SYT1 synaptotagmin I -2.06336
COL6A3 collagen, type VI, alpha 3 -2.05956
UROS uroporphyrinogen III synthase -2.05433
HEXB hexosaminidase B (beta polypeptide) -2.04802
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -2.04265
ZDHHC11B zinc finger, DHHC-type containing 11B -2.04081
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.03395
KDM7A lysine (K)-specific demethylase 7A -2.00744