CRCGN015_MCF10A_48H:O23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetamide 35.0 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

53 genes differentially expressed following the CRCGN015_MCF10A_48H:O23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DLK1 delta-like 1 homolog (Drosophila) 4.59764
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 4.03089
MAMLD1 mastermind-like domain containing 1 3.5137
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.31837
ARID5B AT rich interactive domain 5B (MRF1-like) 2.84248
CHN1 chimerin 1 2.80995
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 2.67624
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 2.56759
TRAF3 TNF receptor-associated factor 3 2.51041
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.48322
CERK ceramide kinase 2.43255
WDR37 WD repeat domain 37 2.37242
SETD1A SET domain containing 1A 2.34996
FAM171A1 family with sequence similarity 171, member A1 2.32477
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2.32374
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.30684
TET3 tet methylcytosine dioxygenase 3 2.30253
ELAC2 elaC ribonuclease Z 2 2.29478
SOCS5 suppressor of cytokine signaling 5 2.23766
SPAG1 sperm associated antigen 1 2.23355
TOMM34 translocase of outer mitochondrial membrane 34 2.23243
CCNO cyclin O 2.2209
ARMCX5 armadillo repeat containing, X-linked 5 2.18928
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 2.16502
POLR2M polymerase (RNA) II (DNA directed) polypeptide M 2.16274
CCNF cyclin F 2.14423
USP6NL USP6 N-terminal like 2.0934
TIMP1 TIMP metallopeptidase inhibitor 1 2.08753
ADGRA3 adhesion G protein-coupled receptor A3 2.0663
AGO2 argonaute RISC catalytic component 2 2.03915
TSC22D1 TSC22 domain family, member 1 2.01524
ZNF532 zinc finger protein 532 2.01154
POLR1D polymerase (RNA) I polypeptide D, 16kDa 2.00255

decreased expression

Symbol Name Standardized Value
LYPLA1 lysophospholipase I -3.53775
CDC20 cell division cycle 20 -3.22714
ZNF136 zinc finger protein 136 -2.61765
RAP2A RAP2A, member of RAS oncogene family -2.53424
S100A8 S100 calcium binding protein A8 -2.4476
MRPL15 mitochondrial ribosomal protein L15 -2.41228
CORO1C coronin, actin binding protein, 1C -2.35868
SCIN scinderin -2.31249
GPX3 glutathione peroxidase 3 -2.21287
CXCL14 chemokine (C-X-C motif) ligand 14 -2.20011
CBR1 carbonyl reductase 1 -2.18381
PLXDC2 plexin domain containing 2 -2.13775
SREK1IP1 SREK1-interacting protein 1 -2.13694
KCNK10 potassium channel, two pore domain subfamily K, member 10 -2.11864
MTMR12 myotubularin related protein 12 -2.1007
PLK2 polo-like kinase 2 -2.08641
STAB1 stabilin 1 -2.06322
CYBA cytochrome b-245, alpha polypeptide -2.06028
LASP1 LIM and SH3 protein 1 -2.04402
HAMP hepcidin antimicrobial peptide -2.03377