CRCGN015_MCF10A_48H:P01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acedapsone 98.29 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN015_MCF10A_48H:P01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
S100A4 S100 calcium binding protein A4 3.84127
TRIM13 tripartite motif containing 13 2.80523
CCDC85B coiled-coil domain containing 85B 2.66609
PRKCD protein kinase C, delta 2.51069
AKR1C3 aldo-keto reductase family 1, member C3 2.46586
RRAGA Ras-related GTP binding A 2.43757
C5 complement component 5 2.29402
ZNF589 zinc finger protein 589 2.28974
HSBP1 heat shock factor binding protein 1 2.23099
SCAND1 SCAN domain containing 1 2.14918
AKR1C1 aldo-keto reductase family 1, member C1 2.13818
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.10959
UBQLN2 ubiquilin 2 2.05495
PPARG peroxisome proliferator-activated receptor gamma 2.014
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 2.00988
AGBL5 ATP/GTP binding protein-like 5 2.00152

decreased expression

Symbol Name Standardized Value
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.29092
TM9SF3 transmembrane 9 superfamily member 3 -4.04128
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.53196
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.8932
MACF1 microtubule-actin crosslinking factor 1 -2.65117
LINC02762 long intergenic non-protein coding RNA 2762 -2.5843
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.52994
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -2.44429
EIF5 eukaryotic translation initiation factor 5 -2.35128
FOXF1 forkhead box F1 -2.10206
MKNK1 MAP kinase interacting serine/threonine kinase 1 -2.08529
EMC1 ER membrane protein complex subunit 1 -2.07479
UBIAD1 UbiA prenyltransferase domain containing 1 -2.04753
PWWP3A PWWP domain containing 3A, DNA repair factor -2.04397
PLK2 polo-like kinase 2 -2.04372
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -2.03183
TTC38 tetratricopeptide repeat domain 38 -2.03175
EIF5B eukaryotic translation initiation factor 5B -2.02459
BBS7 Bardet-Biedl syndrome 7 -2.00528