CRCGN015_MCF10A_48H:P02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acedapsone 32.76 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_MCF10A_48H:P02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WIF1 WNT inhibitory factor 1 7.52028
WFS1 Wolfram syndrome 1 (wolframin) 4.66732
FBXL12 F-box and leucine-rich repeat protein 12 3.7725
ELAC2 elaC ribonuclease Z 2 3.10293
LGALS1 lectin, galactoside-binding, soluble, 1 2.68824
ATG2A autophagy related 2A 2.26426
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 2.26348
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.23464
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.22382
FXYD1 FXYD domain containing ion transport regulator 1 2.19952
APOM apolipoprotein M 2.17288
MYOD1 myogenic differentiation 1 2.1722
MICALL1 MICAL-like 1 2.16074
FBRS fibrosin 2.10069
TXNL4B thioredoxin-like 4B 2.09084
CCDC85B coiled-coil domain containing 85B 2.02672
PEX11A peroxisomal biogenesis factor 11 alpha 2.01128

decreased expression

Symbol Name Standardized Value
HEBP1 heme binding protein 1 -3.04853
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.57858
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.22621
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) -2.19232
CEP85 centrosomal protein 85kDa -2.18655
RGPD2 RANBP2-like and GRIP domain containing 2 -2.17683
CD3E CD3e molecule, epsilon (CD3-TCR complex) -2.16954
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -2.08725
CTPS1 CTP synthase 1 -2.08684
SPATS2 spermatogenesis associated, serine-rich 2 -2.07718
YAP1 Yes-associated protein 1 -2.06329
PCYOX1 prenylcysteine oxidase 1 -2.0548
CD247 CD247 molecule -2.01914
RFC2 replication factor C (activator 1) 2, 40kDa -2.01273