CRCGN015_MCF10A_48H:P12 Gene Set

Dataset	Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category	transcriptomics
Type	small molecule perturbation
Description	megestrol 11.07 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

10 genes differentially expressed following the CRCGN015_MCF10A_48H:P12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol	Name	Standardized Value
MAPK9	mitogen-activated protein kinase 9	3.2182
COQ8A	coenzyme Q8A	2.72145
SIRT3	sirtuin 3	2.40943
PSRC1	proline/serine-rich coiled-coil 1	2.13554
ANKRD10	ankyrin repeat domain 10	2.135
FOCAD	focadhesin	2.10818

decreased expression

Symbol	Name	Standardized Value
S100A8	S100 calcium binding protein A8	-4.69183
RGS2	regulator of G-protein signaling 2	-4.22466
CREG1	cellular repressor of E1A-stimulated genes 1	-3.1419
NCK1	NCK adaptor protein 1	-3.12169