CRCGN015_MCF10A_48H:P15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description uracil mustard 11.27 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_MCF10A_48H:P15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 4.51418
MSRA methionine sulfoxide reductase A 3.45663
ANO10 anoctamin 10 2.57027
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.28883
POLK polymerase (DNA directed) kappa 2.11645
FHL2 four and a half LIM domains 2 2.05422

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -4.13908
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.17726
S100A8 S100 calcium binding protein A8 -2.63275
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.40084
RXYLT1 ribitol xylosyltransferase 1 -2.21696
MAGEA12 melanoma antigen family A12 -2.08985
USP1 ubiquitin specific peptidase 1 -2.0605
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.0353
HMGB2 high mobility group box 2 -2.0245