CRCGN015_MCF10A_48H:P17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description amsonic acid 33.52 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_MCF10A_48H:P17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYLK myosin light chain kinase 4.15391
GRWD1 glutamate-rich WD repeat containing 1 4.02209
AMDHD2 amidohydrolase domain containing 2 2.99588
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.93576
MCOLN1 mucolipin 1 2.83961
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.45888
MAP2K5 mitogen-activated protein kinase kinase 5 2.17722
PNPLA6 patatin-like phospholipase domain containing 6 2.16242
ALX1 ALX homeobox 1 2.06493
XPC xeroderma pigmentosum, complementation group C 2.01409

decreased expression

Symbol Name Standardized Value
MT2A metallothionein 2A -6.45582
MT1X metallothionein 1X -4.39383
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.20559
IGFBP7 insulin-like growth factor binding protein 7 -3.15806
KRT7 keratin 7, type II -2.99479
LOC127933115 uncharacterized LOC127933115 -2.62046
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.36259
PUDP pseudouridine 5'-phosphatase -2.27528
LPXN leupaxin -2.25572
SLBP stem-loop binding protein -2.17962
ENOPH1 enolase-phosphatase 1 -2.17942
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -2.1685
MOSPD2 motile sperm domain containing 2 -2.12578
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -2.09976
TG thyroglobulin -2.06765
MT1E metallothionein 1E -2.05067
ATG101 autophagy related 101 -2.04247
EEF1AKMT3 EEF1A lysine methyltransferase 3 -2.037
ACOT9 acyl-CoA thioesterase 9 -2.00417