CRCGN015_MCF10A_48H:P18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description amsonic acid 11.17 um perturbation at 48 h in MCF10A (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN015_MCF10A_48H:P18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GATA3 GATA binding protein 3 3.34205
GATA2 GATA binding protein 2 2.86913
PRKCQ protein kinase C, theta 2.84432
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.79484
BAMBI BMP and activin membrane-bound inhibitor 2.48011
ELAC2 elaC ribonuclease Z 2 2.39468
BEX3 brain expressed X-linked 3 2.36981
ZNF589 zinc finger protein 589 2.33213
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.14072
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.08948

decreased expression

Symbol Name Standardized Value
CD58 CD58 molecule -4.30854
MSMO1 methylsterol monooxygenase 1 -3.83549
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.51675
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.98623
FASTKD5 FAST kinase domains 5 -2.92593
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.83
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) -2.42291
ZNF136 zinc finger protein 136 -2.31643
ZNF426 zinc finger protein 426 -2.26186
TNRC6B trinucleotide repeat containing 6B -2.25981
PLK2 polo-like kinase 2 -2.22272
MCUR1 mitochondrial calcium uniporter regulator 1 -2.10371
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.05077
ZBTB35 zinc finger and BTB domain containing 35 -2.00421