CRCGN015_MCF10A_48H:P21 Gene Set
Genes
47 genes differentially expressed following the CRCGN015_MCF10A_48H:P21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYL9
|
myosin, light chain 9, regulatory
|
5.03137
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
4.59011
|
|
TPM1
|
tropomyosin 1 (alpha)
|
3.69766
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
3.31081
|
|
HBA1
|
hemoglobin, alpha 1
|
2.80432
|
|
YIPF3
|
Yip1 domain family, member 3
|
2.34632
|
|
RGS2
|
regulator of G-protein signaling 2
|
2.26806
|
|
SLC25A4
|
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
|
2.23081
|
|
FHL2
|
four and a half LIM domains 2
|
2.1801
|
|
ABCC10
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
|
2.12479
|
|
LRP10
|
low density lipoprotein receptor-related protein 10
|
2.10358
|
|
RTL8C
|
retrotransposon Gag like 8C
|
2.04262
|
|
SNX11
|
sorting nexin 11
|
2.02806
|
|
ZNF266
|
zinc finger protein 266
|
2.02058
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ENOPH1
|
enolase-phosphatase 1
|
-4.2341
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.91306
|
|
CCNB2
|
cyclin B2
|
-3.1185
|
|
KIF20A
|
kinesin family member 20A
|
-3.04028
|
|
UBE2C
|
ubiquitin-conjugating enzyme E2C
|
-2.43388
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.42612
|
|
NLRP4
|
NLR family, pyrin domain containing 4
|
-2.42211
|
|
CDKN3
|
cyclin-dependent kinase inhibitor 3
|
-2.3948
|
|
LBR
|
lamin B receptor
|
-2.35903
|
|
BIRC5
|
baculoviral IAP repeat containing 5
|
-2.35828
|
|
HIRIP3
|
HIRA interacting protein 3
|
-2.33422
|
|
PSMG1
|
proteasome (prosome, macropain) assembly chaperone 1
|
-2.29764
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
-2.29207
|
|
MAD2L1
|
MAD2 mitotic arrest deficient-like 1 (yeast)
|
-2.28886
|
|
FBXO5
|
F-box protein 5
|
-2.25629
|
|
HMGB2
|
high mobility group box 2
|
-2.24611
|
|
PBK
|
PDZ binding kinase
|
-2.22892
|
|
CCNA2
|
cyclin A2
|
-2.22722
|
|
SOAT2
|
sterol O-acyltransferase 2
|
-2.18893
|
|
ASF1A
|
anti-silencing function 1A histone chaperone
|
-2.17339
|
|
RACGAP1
|
Rac GTPase activating protein 1
|
-2.16192
|
|
CDK1
|
cyclin-dependent kinase 1
|
-2.12205
|
|
COPS4
|
COP9 signalosome subunit 4
|
-2.08077
|
|
ASF1B
|
anti-silencing function 1B histone chaperone
|
-2.04832
|
|
CCNB1
|
cyclin B1
|
-2.03332
|
|
KIF14
|
kinesin family member 14
|
-2.03061
|
|
LPGAT1
|
lysophosphatidylglycerol acyltransferase 1
|
-2.03015
|
|
KIF18A
|
kinesin family member 18A
|
-2.02254
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.01537
|
|
DONSON
|
downstream neighbor of SON
|
-2.01117
|
|
KIF4A
|
kinesin family member 4A
|
-2.00975
|
|
OIP5
|
Opa interacting protein 5
|
-2.00689
|
|
ESD
|
esterase D
|
-2.00118
|
