| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dibenzo[a,h]pyrene 100.48 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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169 genes differentially expressed following the CRCGN015_MCF10A_48H:P22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 4.94586 |
| FPGS | folylpolyglutamate synthase | 4.51808 |
| WASF3 | WAS protein family, member 3 | 4.17538 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 3.88682 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.85768 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | 3.32033 |
| WASHC5 | WASH complex subunit 5 | 3.25413 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 3.22283 |
| WIF1 | WNT inhibitory factor 1 | 3.12145 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.1168 |
| TBX21 | T-box 21 | 3.0351 |
| CDK9 | cyclin-dependent kinase 9 | 2.9946 |
| MYD88 | myeloid differentiation primary response 88 | 2.95618 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | 2.94987 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.89678 |
| IER3 | immediate early response 3 | 2.87049 |
| SKIC2 | SKI2 subunit of superkiller complex | 2.83346 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.81047 |
| FBXL6 | F-box and leucine-rich repeat protein 6 | 2.75854 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 2.67515 |
| SHFL | shiftless antiviral inhibitor of ribosomal frameshifting | 2.65395 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.64412 |
| UBE2Q1 | ubiquitin-conjugating enzyme E2Q family member 1 | 2.62886 |
| USP6NL | USP6 N-terminal like | 2.55133 |
| TP53I3 | tumor protein p53 inducible protein 3 | 2.54336 |
| TMEM40 | transmembrane protein 40 | 2.53613 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 2.49971 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 2.49371 |
| NUP133 | nucleoporin 133kDa | 2.4855 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) | 2.47062 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 | 2.41867 |
| SARAF | store-operated calcium entry-associated regulatory factor | 2.40881 |
| PRKCD | protein kinase C, delta | 2.40698 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 2.38771 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 2.36118 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 2.2975 |
| TH | tyrosine hydroxylase | 2.28842 |
| SACM1L | SAC1 suppressor of actin mutations 1-like (yeast) | 2.26786 |
| PRR13 | proline rich 13 | 2.26304 |
| GOLGB1 | golgin B1 | 2.23187 |
| ZNF710 | zinc finger protein 710 | 2.22723 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | 2.21654 |
| TMEM53 | transmembrane protein 53 | 2.2108 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 2.19045 |
| GOLGA8N | golgin A8 family, member N | 2.18659 |
| DDRGK1 | DDRGK domain containing 1 | 2.17615 |
| ZFP36 | ZFP36 ring finger protein | 2.17479 |
| SPI1 | Spi-1 proto-oncogene | 2.17383 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | 2.16942 |
| CENPT | centromere protein T | 2.16825 |
| RFTN1 | raftlin, lipid raft linker 1 | 2.16627 |
| INTS3 | integrator complex subunit 3 | 2.16362 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | 2.15529 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 2.15345 |
| NIT1 | nitrilase 1 | 2.1515 |
| VPREB1 | pre-B lymphocyte 1 | 2.13922 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 2.13828 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 2.13349 |
| PLXNB2 | plexin B2 | 2.12188 |
| ZBED2 | zinc finger, BED-type containing 2 | 2.11745 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 2.11019 |
| VAV1 | vav 1 guanine nucleotide exchange factor | 2.09902 |
| IL1B | interleukin 1, beta | 2.08995 |
| HOPX | HOP homeobox | 2.08042 |
| ATG2A | autophagy related 2A | 2.0593 |
| ARHGAP29 | Rho GTPase activating protein 29 | 2.05374 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | 2.05323 |
| TRABD | TraB domain containing | 2.05259 |
| MX1 | MX dynamin-like GTPase 1 | 2.05137 |
| SHARPIN | SHANK-associated RH domain interactor | 2.04557 |
| H2BC21 | H2B clustered histone 21 | 2.04178 |
| MADD | MAP-kinase activating death domain | 2.03234 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | 2.03206 |
| UBA7 | ubiquitin-like modifier activating enzyme 7 | 2.02421 |
| SIRT7 | sirtuin 7 | 2.01914 |
| MAB21L4 | mab-21 like 4 | 2.01487 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 2.01437 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | 2.01365 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 2.00303 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCK | deoxycytidine kinase | -5.58399 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -4.99284 |
| CCNB1 | cyclin B1 | -4.8326 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -4.15437 |
| CCNB2 | cyclin B2 | -4.01514 |
| MELK | maternal embryonic leucine zipper kinase | -3.47202 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -3.46113 |
| STMN1 | stathmin 1 | -3.14733 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -2.94086 |
| CCNA2 | cyclin A2 | -2.9166 |
| CENPU | centromere protein U | -2.89985 |
| PTTG1 | pituitary tumor-transforming 1 | -2.74895 |
| ANXA3 | annexin A3 | -2.73465 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -2.66793 |
| PBK | PDZ binding kinase | -2.66725 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -2.62907 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -2.61712 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.59449 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -2.59401 |
| CDC20 | cell division cycle 20 | -2.59268 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.57895 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | -2.56865 |
| COG2 | component of oligomeric golgi complex 2 | -2.54455 |
| LYRM4 | LYR motif containing 4 | -2.53609 |
| VRK1 | vaccinia related kinase 1 | -2.53097 |
| PCNA | proliferating cell nuclear antigen | -2.51128 |
| RACGAP1 | Rac GTPase activating protein 1 | -2.49563 |
| TTK | TTK protein kinase | -2.46362 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -2.41808 |
| DBF4 | DBF4 zinc finger | -2.40843 |
| CDK1 | cyclin-dependent kinase 1 | -2.39261 |
| MCM6 | minichromosome maintenance complex component 6 | -2.39064 |
| SEH1L | SEH1-like (S. cerevisiae) | -2.37852 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -2.37555 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -2.36876 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -2.36099 |
| COL4A2 | collagen, type IV, alpha 2 | -2.35419 |
| NUP37 | nucleoporin 37kDa | -2.33853 |
| FN1 | fibronectin 1 | -2.33085 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | -2.31941 |
| BLMH | bleomycin hydrolase | -2.30776 |
| MRPL48 | mitochondrial ribosomal protein L48 | -2.30443 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -2.30239 |
| H2AZ1 | H2A.Z variant histone 1 | -2.30048 |
| HMGB2 | high mobility group box 2 | -2.29931 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -2.28607 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -2.27647 |
| METTL18 | methyltransferase like 18 | -2.27024 |
| DHPS | deoxyhypusine synthase | -2.26049 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -2.2567 |
| MRPL42 | mitochondrial ribosomal protein L42 | -2.25592 |
| CLIC4 | chloride intracellular channel 4 | -2.25503 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.22312 |
| ASF1A | anti-silencing function 1A histone chaperone | -2.21099 |
| PAAF1 | proteasomal ATPase-associated factor 1 | -2.19563 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) | -2.19415 |
| UGT8 | UDP glycosyltransferase 8 | -2.19098 |
| TAF9 | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa | -2.18962 |
| ECI2 | enoyl-CoA delta isomerase 2 | -2.18803 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.18714 |
| TRH | thyrotropin-releasing hormone | -2.17498 |
| ANAPC15 | anaphase promoting complex subunit 15 | -2.17426 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -2.16889 |
| TPX2 | TPX2, microtubule-associated | -2.16096 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -2.15235 |
| EXOSC9 | exosome component 9 | -2.14485 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -2.13386 |
| CKAP2 | cytoskeleton associated protein 2 | -2.12516 |
| ERH | enhancer of rudimentary homolog (Drosophila) | -2.12134 |
| SLC25A46 | solute carrier family 25, member 46 | -2.1202 |
| FBXO5 | F-box protein 5 | -2.09841 |
| CBR3 | carbonyl reductase 3 | -2.09816 |
| MED28 | mediator complex subunit 28 | -2.08548 |
| CALU | calumenin | -2.08397 |
| AAAS | achalasia, adrenocortical insufficiency, alacrimia | -2.08242 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -2.08042 |
| TXNDC5 | thioredoxin domain containing 5 (endoplasmic reticulum) | -2.06658 |
| CENPN | centromere protein N | -2.06414 |
| BUD23 | BUD23 rRNA methyltransferase and ribosome maturation factor | -2.06403 |
| ARF5 | ADP-ribosylation factor 5 | -2.05574 |
| CENPA | centromere protein A | -2.05397 |
| PAQR3 | progestin and adipoQ receptor family member III | -2.05127 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.04614 |
| HMG20B | high mobility group 20B | -2.04313 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -2.02401 |
| CMC2 | C-x(9)-C motif containing 2 | -2.02314 |
| MTMR2 | myotubularin related protein 2 | -2.01563 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) | -2.0116 |
| ALG9 | ALG9, alpha-1,2-mannosyltransferase | -2.00761 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -2.0005 |
