| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dibenzo[a,h]pyrene 33.49 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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87 genes differentially expressed following the CRCGN015_MCF10A_48H:P23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 4.33291 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 4.23575 |
| KLHL21 | kelch-like family member 21 | 3.61179 |
| FGFR4 | fibroblast growth factor receptor 4 | 3.51617 |
| IER3 | immediate early response 3 | 3.15071 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.99829 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 2.93807 |
| USP6NL | USP6 N-terminal like | 2.92751 |
| PRKCD | protein kinase C, delta | 2.63265 |
| DTX2 | deltex 2, E3 ubiquitin ligase | 2.60793 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.60214 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 2.51925 |
| SLC6A11 | solute carrier family 6 (neurotransmitter transporter), member 11 | 2.51778 |
| PRSS22 | protease, serine, 22 | 2.49988 |
| TGM1 | transglutaminase 1 | 2.4379 |
| SQSTM1 | sequestosome 1 | 2.40739 |
| LTC4S | leukotriene C4 synthase | 2.33841 |
| CYB5R1 | cytochrome b5 reductase 1 | 2.31038 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2.30571 |
| AACS | acetoacetyl-CoA synthetase | 2.29492 |
| ADAM8 | ADAM metallopeptidase domain 8 | 2.26991 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 2.21547 |
| CLTC | clathrin, heavy chain (Hc) | 2.2001 |
| CRCT1 | cysteine-rich C-terminal 1 | 2.19017 |
| SH2D4A | SH2 domain containing 4A | 2.18514 |
| ATG2A | autophagy related 2A | 2.15436 |
| BECN1 | beclin 1, autophagy related | 2.11598 |
| LIN7A | lin-7 homolog A (C. elegans) | 2.11322 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | 2.11198 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | 2.09275 |
| TGM3 | transglutaminase 3 | 2.08421 |
| UBE2Q1 | ubiquitin-conjugating enzyme E2Q family member 1 | 2.0839 |
| AKTIP | AKT interacting protein | 2.06369 |
| KLK13 | kallikrein-related peptidase 13 | 2.06265 |
| DPYSL2 | dihydropyrimidinase-like 2 | 2.04744 |
| SLC35F6 | solute carrier family 35, member F6 | 2.03826 |
| LOC124908558 | X antigen family member 1-like | 2.03725 |
| CRNN | cornulin | 2.03031 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 | 2.02998 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.02822 |
| SGSH | N-sulfoglucosamine sulfohydrolase | 2.0272 |
| AKAP17A | A kinase (PRKA) anchor protein 17A | 2.02423 |
| LOC124906748 | beta-defensin 4A | 2.01041 |
| CPZ | carboxypeptidase Z | 2.00811 |
| EML3 | echinoderm microtubule associated protein like 3 | 2.00112 |
| MBD1 | methyl-CpG binding domain protein 1 | 2.00094 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 | -4.49284 |
| TUBB6 | tubulin, beta 6 class V | -4.20863 |
| PCNA | proliferating cell nuclear antigen | -3.48158 |
| S100A8 | S100 calcium binding protein A8 | -3.35943 |
| MT2A | metallothionein 2A | -3.34509 |
| ATP11B | ATPase, class VI, type 11B | -3.20379 |
| VIM | vimentin | -3.06869 |
| PLS1 | plastin 1 | -3.06043 |
| CCNB2 | cyclin B2 | -2.74246 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -2.74127 |
| BIRC5 | baculoviral IAP repeat containing 5 | -2.69754 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | -2.60207 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -2.48942 |
| EGR1 | early growth response 1 | -2.46593 |
| KIF15 | kinesin family member 15 | -2.4612 |
| NUP85 | nucleoporin 85kDa | -2.40001 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa | -2.39205 |
| CDC20 | cell division cycle 20 | -2.34432 |
| CDK4 | cyclin-dependent kinase 4 | -2.32433 |
| NDC80 | NDC80 kinetochore complex component | -2.27745 |
| CCNA2 | cyclin A2 | -2.27301 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.26716 |
| TTK | TTK protein kinase | -2.24388 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.19796 |
| EXTL2 | exostosin-like glycosyltransferase 2 | -2.19282 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.18026 |
| ATG5 | autophagy related 5 | -2.16333 |
| FBXO5 | F-box protein 5 | -2.14466 |
| LMNB1 | lamin B1 | -2.13971 |
| RBMX | RNA binding motif protein, X-linked | -2.10767 |
| DEPDC1 | DEP domain containing 1 | -2.10413 |
| CDCA8 | cell division cycle associated 8 | -2.09441 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | -2.09187 |
| MDN1 | MDN1, midasin homolog (yeast) | -2.08068 |
| CHIT1 | chitinase 1 (chitotriosidase) | -2.05347 |
| MT1X | metallothionein 1X | -2.04257 |
| DHPS | deoxyhypusine synthase | -2.0371 |
| STOML2 | stomatin (EPB72)-like 2 | -2.02562 |
| ZNF184 | zinc finger protein 184 | -2.02484 |
| CASP8AP2 | caspase 8 associated protein 2 | -2.01005 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.00693 |
