| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dibenzo[a,h]pyrene 11.16 um perturbation at 48 h in MCF10A (Carcinogenome) |
| Similar Terms | |
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137 genes differentially expressed following the CRCGN015_MCF10A_48H:P24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 4.24676 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.68142 |
| UBQLN2 | ubiquilin 2 | 3.33517 |
| FZD1 | frizzled class receptor 1 | 3.26179 |
| TRIM13 | tripartite motif containing 13 | 3.1688 |
| GTF2B | general transcription factor IIB | 2.86225 |
| ELAC2 | elaC ribonuclease Z 2 | 2.7643 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 2.71836 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 2.6969 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 2.65701 |
| WDR26 | WD repeat domain 26 | 2.64894 |
| PRKCD | protein kinase C, delta | 2.64063 |
| UBE2Q1 | ubiquitin-conjugating enzyme E2Q family member 1 | 2.62845 |
| GNG5 | guanine nucleotide binding protein (G protein), gamma 5 | 2.60101 |
| MAP7 | microtubule-associated protein 7 | 2.60043 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.55424 |
| DENND4B | DENN/MADD domain containing 4B | 2.51221 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.48456 |
| WASF3 | WAS protein family, member 3 | 2.46983 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.44444 |
| METTL22 | methyltransferase like 22 | 2.39049 |
| MBD1 | methyl-CpG binding domain protein 1 | 2.3874 |
| BLCAP | bladder cancer associated protein | 2.33166 |
| NGRN | neugrin, neurite outgrowth associated | 2.31645 |
| GLRX2 | glutaredoxin 2 | 2.30985 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.30678 |
| CCDC92 | coiled-coil domain containing 92 | 2.30189 |
| STXBP1 | syntaxin binding protein 1 | 2.30123 |
| IER3 | immediate early response 3 | 2.26864 |
| FGFR4 | fibroblast growth factor receptor 4 | 2.26748 |
| STK25 | serine/threonine kinase 25 | 2.25707 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | 2.24364 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 | 2.23836 |
| RGS18 | regulator of G-protein signaling 18 | 2.23735 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.22677 |
| MOK | MOK protein kinase | 2.22222 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.19394 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | 2.19296 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 2.17316 |
| CSRNP2 | cysteine-serine-rich nuclear protein 2 | 2.16912 |
| PLIN1 | perilipin 1 | 2.15524 |
| CAPN10 | calpain 10 | 2.14436 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 2.14031 |
| PCDHGA5 | protocadherin gamma subfamily A, 5 | 2.13956 |
| SSUH2 | ssu-2 homolog (C. elegans) | 2.13297 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 2.12821 |
| STXBP2 | syntaxin binding protein 2 | 2.11272 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | 2.10847 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 2.10181 |
| ZNF263 | zinc finger protein 263 | 2.09554 |
| NPTX2 | neuronal pentraxin II | 2.09063 |
| RWDD2A | RWD domain containing 2A | 2.08613 |
| ABHD4 | abhydrolase domain containing 4 | 2.08451 |
| CEL | carboxyl ester lipase | 2.08156 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) | 2.07744 |
| ZNF710 | zinc finger protein 710 | 2.07688 |
| CENPT | centromere protein T | 2.06744 |
| MOSPD1 | motile sperm domain containing 1 | 2.06627 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 2.0641 |
| DPH2 | DPH2 homolog (S. cerevisiae) | 2.04139 |
| GCC1 | GRIP and coiled-coil domain containing 1 | 2.03958 |
| BECN1 | beclin 1, autophagy related | 2.03244 |
| NIT1 | nitrilase 1 | 2.02883 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 2.02201 |
| EIF2B5 | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa | 2.01967 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 2.01156 |
| WDR37 | WD repeat domain 37 | 2.00542 |
| Symbol | Name | Standardized Value |
|---|---|---|
| S100A8 | S100 calcium binding protein A8 | -3.43314 |
| CCNB2 | cyclin B2 | -3.29126 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.23757 |
| LETMD1 | LETM1 domain containing 1 | -2.85177 |
| CDC20 | cell division cycle 20 | -2.81169 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -2.74667 |
| PCNA | proliferating cell nuclear antigen | -2.71122 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | -2.6996 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.6809 |
| STMN1 | stathmin 1 | -2.68049 |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | -2.64751 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -2.6281 |
| S100B | S100 calcium binding protein B | -2.60016 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -2.59476 |
| BIRC5 | baculoviral IAP repeat containing 5 | -2.56965 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | -2.50515 |
| GPM6B | glycoprotein M6B | -2.48448 |
| CCNA2 | cyclin A2 | -2.48126 |
| CBR3 | carbonyl reductase 3 | -2.4654 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -2.4514 |
| COL4A2 | collagen, type IV, alpha 2 | -2.43877 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) | -2.40229 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -2.39881 |
| KIF14 | kinesin family member 14 | -2.39471 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -2.39296 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | -2.38346 |
| MELK | maternal embryonic leucine zipper kinase | -2.37336 |
| CDK1 | cyclin-dependent kinase 1 | -2.3678 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.36744 |
| CDC45 | cell division cycle 45 | -2.36348 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | -2.35409 |
| NRN1 | neuritin 1 | -2.32293 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | -2.25906 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.25697 |
| SLC35A5 | solute carrier family 35, member A5 | -2.25617 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -2.24704 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 | -2.24037 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -2.23695 |
| ATG3 | autophagy related 3 | -2.23086 |
| CENPM | centromere protein M | -2.2298 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -2.22339 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -2.21798 |
| FBXO7 | F-box protein 7 | -2.18416 |
| EGR1 | early growth response 1 | -2.17443 |
| IL1RAP | interleukin 1 receptor accessory protein | -2.14292 |
| ASF1B | anti-silencing function 1B histone chaperone | -2.11222 |
| DDTL | D-dopachrome tautomerase-like | -2.10712 |
| MCM6 | minichromosome maintenance complex component 6 | -2.10205 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -2.09361 |
| TTK | TTK protein kinase | -2.09083 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -2.08268 |
| NEK2 | NIMA-related kinase 2 | -2.07253 |
| BLMH | bleomycin hydrolase | -2.0716 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -2.06182 |
| TMPO | thymopoietin | -2.05964 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -2.05883 |
| MRPS27 | mitochondrial ribosomal protein S27 | -2.05744 |
| PBK | PDZ binding kinase | -2.05461 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -2.05092 |
| RACGAP1 | Rac GTPase activating protein 1 | -2.05012 |
| ABCB7 | ATP-binding cassette, sub-family B (MDR/TAP), member 7 | -2.04785 |
| ZIC1 | Zic family member 1 | -2.03954 |
| FCGBP | Fc fragment of IgG binding protein | -2.03661 |
| ELP3 | elongator acetyltransferase complex subunit 3 | -2.02876 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.02083 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | -2.01724 |
| H2AC25 | H2A clustered histone 25 | -2.01386 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -2.01383 |
| FANCC | Fanconi anemia, complementation group C | -2.00493 |
| LMNB1 | lamin B1 | -2.00114 |
