CRCGN016_MCF10A.TP53.M_24H:A04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:A04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 4.17663
C2CD2 C2 calcium-dependent domain containing 2 3.83627
SPAG4 sperm associated antigen 4 3.17573
SNAP25 synaptosomal-associated protein, 25kDa 3.16703
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.9882
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.92978
ACAA1 acetyl-CoA acyltransferase 1 2.6077
COMP cartilage oligomeric matrix protein 2.35017
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.34713
STMN2 stathmin 2 2.15072
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.07317

decreased expression

Symbol Name Standardized Value
DIPK1A divergent protein kinase domain 1A -3.94183
HMG20B high mobility group 20B -3.37303
DSG2 desmoglein 2 -3.2978
GTPBP8 GTP-binding protein 8 (putative) -3.21033
CCNB2 cyclin B2 -3.02697
MSN moesin -3.01677
CD44 CD44 molecule (Indian blood group) -2.94722
FPGS folylpolyglutamate synthase -2.7091
KDM3A lysine (K)-specific demethylase 3A -2.67703
BASP1 brain abundant, membrane attached signal protein 1 -2.56337
GRWD1 glutamate-rich WD repeat containing 1 -2.45223
DCK deoxycytidine kinase -2.15207
COTL1 coactosin-like F-actin binding protein 1 -2.10573
EEIG1 estrogen-induced osteoclastogenesis regulator 1 -2.00893