CRCGN016_MCF10A.TP53.M_24H:A05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:A05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
IGFBP3 insulin-like growth factor binding protein 3 3.91082
PRKCH protein kinase C, eta 3.11298
CHEK1 checkpoint kinase 1 2.55632
CDCA4 cell division cycle associated 4 2.48004
FBXL12 F-box and leucine-rich repeat protein 12 2.19747

decreased expression

Symbol Name Standardized Value
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.93608
MAPK13 mitogen-activated protein kinase 13 -3.71547
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.62698
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.16713
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.90208
COTL1 coactosin-like F-actin binding protein 1 -2.65737
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.54938
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.05855