CRCGN016_MCF10A.TP53.M_24H:A07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,2',3,5',6-pentachloro-1,1'-biphenyl 98.12 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:A07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.79265
PPARG peroxisome proliferator-activated receptor gamma 4.54424
TOMM34 translocase of outer mitochondrial membrane 34 3.64374
BACE2 beta-site APP-cleaving enzyme 2 3.0672
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 2.52331
BAMBI BMP and activin membrane-bound inhibitor 2.231
ACAA1 acetyl-CoA acyltransferase 1 2.22182
MELK maternal embryonic leucine zipper kinase 2.18645
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.08918

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -4.66077
MTERF3 mitochondrial transcription termination factor 3 -2.88711
NPDC1 neural proliferation, differentiation and control, 1 -2.74404
THAP11 THAP domain containing 11 -2.46287
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.18092
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.07062