CRCGN016_MCF10A.TP53.M_24H:A08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,2',3,5',6-pentachloro-1,1'-biphenyl 32.71 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:A08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.37074
GARRE1 granule associated Rac and RHOG effector 1 2.93742
TBX2 T-box 2 2.80667
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.35976
ACAA1 acetyl-CoA acyltransferase 1 2.13681
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.11888
STK25 serine/threonine kinase 25 2.06843

decreased expression

Symbol Name Standardized Value
DYNLT3 dynein, light chain, Tctex-type 3 -4.73042
DNM1L dynamin 1-like -4.26733
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.60521
CORO1A coronin, actin binding protein, 1A -2.49655
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -2.18186
ZNF322 zinc finger protein 322 -2.08045