CRCGN016_MCF10A.TP53.M_24H:A09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,2',3,5',6-pentachloro-1,1'-biphenyl 10.9 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:A09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 5.26952
TSEN2 TSEN2 tRNA splicing endonuclease subunit 4.92292
OXSR1 oxidative stress responsive 1 4.2357
MINDY1 MINDY lysine 48 deubiquitinase 1 3.44096
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.18558
ACAA1 acetyl-CoA acyltransferase 1 2.17494
TPD52L2 tumor protein D52-like 2 2.05324

decreased expression

Symbol Name Standardized Value
MPC2 mitochondrial pyruvate carrier 2 -4.35427
MSMO1 methylsterol monooxygenase 1 -4.30821
PSIP1 PC4 and SFRS1 interacting protein 1 -3.80972
NUSAP1 nucleolar and spindle associated protein 1 -3.31561
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.06366
PCCB propionyl CoA carboxylase, beta polypeptide -2.85157
KRT14 keratin 14, type I -2.69026
GRN granulin -2.54274
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.28701
HOXA5 homeobox A5 -2.27615
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.09346