CRCGN016_MCF10A.TP53.M_24H:A10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-benzyl 2-butyl phthalate 101.51 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:A10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 3.50538
EAPP E2F-associated phosphoprotein 3.39787
AMDHD2 amidohydrolase domain containing 2 3.20553
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.04712
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.93469
SPAG4 sperm associated antigen 4 2.75205
TLCD3A TLC domain containing 3A 2.45552
PNOC prepronociceptin 2.04003
MOK MOK protein kinase 2.02826
COMP cartilage oligomeric matrix protein 2.01894

decreased expression

Symbol Name Standardized Value
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.22023
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.56799
PLK1 polo-like kinase 1 -3.50543
TNIP1 TNFAIP3 interacting protein 1 -3.30994
KIF20A kinesin family member 20A -2.81129
LDHD lactate dehydrogenase D -2.74455
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.58201
SGK1 serum/glucocorticoid regulated kinase 1 -2.4199
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.20572
NOSIP nitric oxide synthase interacting protein -2.17545
PSENEN presenilin enhancer gamma secretase subunit -2.17381
TBCB tubulin folding cofactor B -2.07418
TMEM147 transmembrane protein 147 -2.05181
GDF15 growth differentiation factor 15 -2.03464