CRCGN016_MCF10A.TP53.M_24H:A14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,2',4,4',5,5'-hexachloro-1,1'-biphenyl 32.84 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

25 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:A14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 5.13197
CCP110 centriolar coiled coil protein 110kDa 4.73875
CARMIL1 capping protein regulator and myosin 1 linker 1 4.71374
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.14665
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 3.36593
ACAA1 acetyl-CoA acyltransferase 1 2.84226
KDM5D lysine (K)-specific demethylase 5D 2.78142
CBR1 carbonyl reductase 1 2.63322
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.60222
GSTZ1 glutathione S-transferase zeta 1 2.56073
EAPP E2F-associated phosphoprotein 2.46217
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.12598
SYNE2 spectrin repeat containing, nuclear envelope 2 2.09444
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.07042

decreased expression

Symbol Name Standardized Value
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.73201
CCNB2 cyclin B2 -3.43093
TIMP1 TIMP metallopeptidase inhibitor 1 -3.31058
THAP11 THAP domain containing 11 -2.33099
NRIP1 nuclear receptor interacting protein 1 -2.26916
STEAP1 six transmembrane epithelial antigen of the prostate 1 -2.19152
LDHD lactate dehydrogenase D -2.18076
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.13974
KRT14 keratin 14, type I -2.12465
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.08532
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.04122