CRCGN016_MCF10A.TP53.M_24H:A20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-hydroxy-2-acetylamino?fluorene 33.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

1071 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:A20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 9.8826
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 9.09667
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 9.07106
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 8.85866
TXNRD1 thioredoxin reductase 1 8.46979
TP53BP2 tumor protein p53 binding protein 2 7.97117
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 7.41136
AARS1 alanyl-tRNA synthetase 1 7.40957
GLRX glutaredoxin (thioltransferase) 7.36614
CHIC2 cysteine-rich hydrophobic domain 2 6.9761
TICAM1 toll-like receptor adaptor molecule 1 6.9561
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 6.7171
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 6.70663
TXLNA taxilin alpha 6.43659
LRP10 low density lipoprotein receptor-related protein 10 6.31722
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 6.18878
CARS1 cysteinyl-tRNA synthetase 1 6.06283
PSAT1 phosphoserine aminotransferase 1 6.05078
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 5.95554
ABHD4 abhydrolase domain containing 4 5.7709
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 5.71284
ASNS asparagine synthetase (glutamine-hydrolyzing) 5.69406
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 5.59362
GFPT1 glutamine--fructose-6-phosphate transaminase 1 5.57038
GARS1 glycyl-tRNA synthetase 1 5.43168
RAP1GAP RAP1 GTPase activating protein 5.35446
PYCR1 pyrroline-5-carboxylate reductase 1 5.29887
TRIB3 tribbles pseudokinase 3 5.27309
NDEL1 nudE neurodevelopment protein 1-like 1 5.05401
PHGDH phosphoglycerate dehydrogenase 5.00269
KLHL21 kelch-like family member 21 4.9208
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 4.9192
LOC128125814 uncharacterized LOC128125814 4.8525
RGS2 regulator of G-protein signaling 2 4.80805
STXBP1 syntaxin binding protein 1 4.80801
VSIG2 V-set and immunoglobulin domain containing 2 4.79153
WIF1 WNT inhibitory factor 1 4.78892
CDPF1 cysteine-rich, DPF motif domain containing 1 4.77022
TERF2IP telomeric repeat binding factor 2, interacting protein 4.75379
MINDY1 MINDY lysine 48 deubiquitinase 1 4.73858
YARS1 tyrosyl-tRNA synthetase 1 4.72853
TUFT1 tuftelin 1 4.72451
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 4.68295
ATF4 activating transcription factor 4 4.66105
XPOT exportin, tRNA 4.61598
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 4.53342
SPRR2B small proline-rich protein 2B 4.50368
TES testin LIM domain protein 4.41146
STAMBP STAM binding protein 4.38687
BLCAP bladder cancer associated protein 4.37596
WFS1 Wolfram syndrome 1 (wolframin) 4.37315
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 4.34347
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 4.34302
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.33116
MICALL1 MICAL-like 1 4.31936
IL36G interleukin 36, gamma 4.29483
INTS3 integrator complex subunit 3 4.26302
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 4.19018
CTSL cathepsin L 4.17605
CRCT1 cysteine-rich C-terminal 1 4.13715
WARS1 tryptophanyl-tRNA synthetase 1 4.12558
ALAS1 5'-aminolevulinate synthase 1 4.10615
FYN FYN proto-oncogene, Src family tyrosine kinase 4.10417
SQSTM1 sequestosome 1 4.05088
SARS1 seryl-tRNA synthetase 1 3.96034
ZCCHC8 zinc finger, CCHC domain containing 8 3.95758
KEAP1 kelch-like ECH-associated protein 1 3.95693
FHL2 four and a half LIM domains 2 3.95126
IGHMBP2 immunoglobulin mu binding protein 2 3.95085
IFRD1 interferon-related developmental regulator 1 3.94987
CANT1 calcium activated nucleotidase 1 3.94344
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 3.89787
GCC1 GRIP and coiled-coil domain containing 1 3.85124
NUPR1 nuclear protein, transcriptional regulator, 1 3.8346
MBD1 methyl-CpG binding domain protein 1 3.83332
PKP1 plakophilin 1 3.82762
GTPBP2 GTP binding protein 2 3.81562
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.80698
LOC102724560 cystathionine beta-synthase 3.78884
UGDH UDP-glucose 6-dehydrogenase 3.7683
ATF3 activating transcription factor 3 3.7339
ZNF212 zinc finger protein 212 3.71391
LYRM1 LYR motif containing 1 3.71002
CAMTA2 calmodulin binding transcription activator 2 3.70001
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 3.69677
UPP1 uridine phosphorylase 1 3.69258
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 3.6831
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 3.68194
TSC1 tuberous sclerosis 1 3.6513
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 3.64363
KRT16 keratin 16, type I 3.62641
EDN1 endothelin 1 3.60978
MARS1 methionyl-tRNA synthetase 1 3.60903
GADD45B growth arrest and DNA-damage-inducible, beta 3.59462
ITPKC inositol-trisphosphate 3-kinase C 3.59376
ARMCX3 armadillo repeat containing, X-linked 3 3.57853
INPP1 inositol polyphosphate-1-phosphatase 3.56603
USP6NL USP6 N-terminal like 3.51947
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 3.49119
TMEM40 transmembrane protein 40 3.48024
GMEB2 glucocorticoid modulatory element binding protein 2 3.47405
ECM1 extracellular matrix protein 1 3.43946
SNAP25 synaptosomal-associated protein, 25kDa 3.43756
CSRNP2 cysteine-serine-rich nuclear protein 2 3.43246
LONP1 lon peptidase 1, mitochondrial 3.42474
DUSP14 dual specificity phosphatase 14 3.42373
RRAGC Ras-related GTP binding C 3.42246
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 3.41906
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.39978
WIPI1 WD repeat domain, phosphoinositide interacting 1 3.39916
PPP4R1 protein phosphatase 4, regulatory subunit 1 3.39476
TARS1 threonyl-tRNA synthetase 1 3.37498
KRT34 keratin 34, type I 3.36054
NARS1 asparaginyl-tRNA synthetase 1 3.35706
TMCC2 transmembrane and coiled-coil domain family 2 3.33255
PHLDA3 pleckstrin homology-like domain, family A, member 3 3.33253
UBAP1 ubiquitin associated protein 1 3.29272
NFE2L1 nuclear factor, erythroid 2-like 1 3.28159
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 3.27201
GABARAPL1 GABA(A) receptor-associated protein like 1 3.2703
BAMBI BMP and activin membrane-bound inhibitor 3.2646
COMP cartilage oligomeric matrix protein 3.25693
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 3.2565
CDSN corneodesmosin 3.25107
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.25014
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 3.22639
PPP1R15A protein phosphatase 1, regulatory subunit 15A 3.20683
RAB11FIP1 RAB11 family interacting protein 1 (class I) 3.20019
TWF2 twinfilin actin binding protein 2 3.17244
OXSR1 oxidative stress responsive 1 3.16339
TFE3 transcription factor binding to IGHM enhancer 3 3.15878
TGM1 transglutaminase 1 3.12452
BSDC1 BSD domain containing 1 3.10433
IL36RN interleukin 36 receptor antagonist 3.09978
NUP58 nucleoporin 58 3.08015
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 3.07728
ABHD6 abhydrolase domain containing 6 3.07316
NPC1 Niemann-Pick disease, type C1 3.0658
LARP6 La ribonucleoprotein domain family, member 6 3.06392
CEMIP2 cell migration inducing hyaluronidase 2 3.05876
CLDN4 claudin 4 3.05529
BCL2L13 BCL2-like 13 (apoptosis facilitator) 3.04905
REEP4 receptor accessory protein 4 3.0432
SPRR1A small proline-rich protein 1A 3.03918
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 3.03835
SLC30A1 solute carrier family 30 (zinc transporter), member 1 3.03403
FBXO46 F-box protein 46 3.03195
GATAD2A GATA zinc finger domain containing 2A 3.01651
ARMCX6 armadillo repeat containing, X-linked 6 3.00997
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 3.00811
TNIP1 TNFAIP3 interacting protein 1 3.00142
PHF21A PHD finger protein 21A 3.00036
AMOTL2 angiomotin like 2 2.98358
TJP1 tight junction protein 1 2.98331
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.97775
FXR2 fragile X mental retardation, autosomal homolog 2 2.96905
RIOK3 RIO kinase 3 2.96285
ACBD3 acyl-CoA binding domain containing 3 2.96152
KDM4A lysine (K)-specific demethylase 4A 2.96143
AEN apoptosis enhancing nuclease 2.94657
CHMP4B charged multivesicular body protein 4B 2.94564
HBEGF heparin-binding EGF-like growth factor 2.94451
RNF103 ring finger protein 103 2.93615
PRSS8 protease, serine, 8 2.93243
CLDN7 claudin 7 2.92762
KLK5 kallikrein-related peptidase 5 2.9223
GATA2 GATA binding protein 2 2.91932
IST1 increased sodium tolerance 1 homolog (yeast) 2.89733
GAA glucosidase, alpha; acid 2.89143
MISP mitotic spindle positioning 2.89064
KRT17 keratin 17, type I 2.88406
IL4R interleukin 4 receptor 2.87442
ZFAND3 zinc finger, AN1-type domain 3 2.87178
PDLIM2 PDZ and LIM domain 2 (mystique) 2.86963
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.86412
ZMPSTE24 zinc metallopeptidase STE24 2.84723
ITPKB inositol-trisphosphate 3-kinase B 2.83989
CALCOCO1 calcium binding and coiled-coil domain 1 2.79849
NOTCH1 notch 1 2.7847
ZBTB35 zinc finger and BTB domain containing 35 2.77517
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.76771
IL1A interleukin 1, alpha 2.76706
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough 2.76548
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 2.76147
STC2 stanniocalcin 2 2.75894
EPHX3 epoxide hydrolase 3 2.75525
IER5 immediate early response 5 2.75452
SOX4 SRY (sex determining region Y)-box 4 2.75249
RUSC2 RUN and SH3 domain containing 2 2.75061
KRT6B keratin 6B, type II 2.7501
RUNDC3A RUN domain containing 3A 2.74999
PDGFA platelet-derived growth factor alpha polypeptide 2.74975
TMEM268 transmembrane protein 268 2.74967
ARPC5L actin related protein 2/3 complex, subunit 5-like 2.73296
RABAC1 Rab acceptor 1 (prenylated) 2.72815
LOC128125822 uncharacterized LOC128125822 2.72596
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 2.72468
LGI1 leucine-rich, glioma inactivated 1 2.72378
WHR1 winged helix repair factor 1 2.72208
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.7136
DSG3 desmoglein 3 2.69876
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.6979
FSTL1 follistatin-like 1 2.6972
HDLBP high density lipoprotein binding protein 2.69472
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 2.69453
REEP1 receptor accessory protein 1 2.68907
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 2.68904
HSPA13 heat shock protein 70kDa family, member 13 2.67424
FGF9 fibroblast growth factor 9 2.66541
INHBE inhibin, beta E 2.66482
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.66338
ATMIN ATM interactor 2.66247
ZNF410 zinc finger protein 410 2.66048
GMPPA GDP-mannose pyrophosphorylase A 2.65959
RALGDS ral guanine nucleotide dissociation stimulator 2.64518
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.64496
NDRG4 NDRG family member 4 2.64447
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 2.63894
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 2.61481
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.61403
RAB11FIP5 RAB11 family interacting protein 5 (class I) 2.60869
INPPL1 inositol polyphosphate phosphatase-like 1 2.60268
KIFC3 kinesin family member C3 2.60149
ATOSB atos homolog B 2.60107
SLC35B1 solute carrier family 35, member B1 2.59719
SPATA2L spermatogenesis associated 2-like 2.59256
IRF6 interferon regulatory factor 6 2.58131
UFM1 ubiquitin-fold modifier 1 2.57973
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 2.57854
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.57425
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 2.56834
NECTIN2 nectin cell adhesion molecule 2 2.56697
SPRR1B small proline-rich protein 1B 2.56442
DRC4 dynein regulatory complex subunit 4 2.55867
PSEN1 presenilin 1 2.55685
SKIC2 SKI2 subunit of superkiller complex 2.55524
TTC4 tetratricopeptide repeat domain 4 2.54955
CTAGE8 CTAGE family, member 8 2.5485
MKNK2 MAP kinase interacting serine/threonine kinase 2 2.54448
G0S2 G0/G1 switch 2 2.53971
LOC114841035 uncharacterized LOC114841035 2.53287
SPAG7 sperm associated antigen 7 2.53192
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2.53124
RAP1GAP2 RAP1 GTPase activating protein 2 2.53013
WHRN whirlin 2.52896
NUCB2 nucleobindin 2 2.51467
CCDC92 coiled-coil domain containing 92 2.51245
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.51205
PI3 peptidase inhibitor 3, skin-derived 2.50987
PLAUR plasminogen activator, urokinase receptor 2.50932
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.50672
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 2.50639
KRT1 keratin 1, type II 2.50368
BLVRB biliverdin reductase B 2.49963
LIMS2 LIM and senescent cell antigen-like domains 2 2.4992
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 2.49779
ULBP2 UL16 binding protein 2 2.49736
PRAF2 PRA1 domain family, member 2 2.49621
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.49083
RBM6 RNA binding motif protein 6 2.48962
SMG5 SMG5 nonsense mediated mRNA decay factor 2.48724
APOL6 apolipoprotein L, 6 2.48663
OCLN occludin 2.48628
CCPG1 cell cycle progression 1 2.48348
LOC122526780 uncharacterized LOC122526780 2.4825
ASS1 argininosuccinate synthase 1 2.47912
NLRX1 NLR family member X1 2.47477
MYOD1 myogenic differentiation 1 2.47347
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 2.46696
EVPL envoplakin 2.46184
RING1 ring finger protein 1 2.4617
PLEKHO2 pleckstrin homology domain containing, family O member 2 2.46103
KIF13B kinesin family member 13B 2.46066
ICAM1 intercellular adhesion molecule 1 2.45399
CSRP1 cysteine and glycine-rich protein 1 2.45122
RNF220 ring finger protein 220 2.44787
IL22RA1 interleukin 22 receptor, alpha 1 2.44668
N4BP1 NEDD4 binding protein 1 2.4436
LCAT lecithin-cholesterol acyltransferase 2.44231
BBC3 BCL2 binding component 3 2.44022
LAMB3 laminin, beta 3 2.43732
STX5 syntaxin 5 2.43534
PROM1 prominin 1 2.42916
TBL1X transducin (beta)-like 1X-linked 2.42894
TRIM16 tripartite motif containing 16 2.4285
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.42807
AKTIP AKT interacting protein 2.42211
LYPD3 LY6/PLAUR domain containing 3 2.421
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 2.41612
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.41326
IRGQ immunity-related GTPase family, Q 2.41274
TRPM4 transient receptor potential cation channel, subfamily M, member 4 2.41186
INAVA innate immunity activator 2.41166
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.40957
TRIM45 tripartite motif containing 45 2.40804
NRBF2 nuclear receptor binding factor 2 2.40096
KDM6B lysine (K)-specific demethylase 6B 2.3978
CLIP1 CAP-GLY domain containing linker protein 1 2.39729
GPC1 glypican 1 2.39631
IP6K1 inositol hexakisphosphate kinase 1 2.39525
BDKRB2 bradykinin receptor B2 2.38885
COG4 component of oligomeric golgi complex 4 2.38489
CMTR1 cap methyltransferase 1 2.38473
LSR lipolysis stimulated lipoprotein receptor 2.38355
CNKSR3 CNKSR family member 3 2.38269
MYT1 myelin transcription factor 1 2.3804
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 2.37958
HYOU1 hypoxia up-regulated 1 2.37836
RNF10 ring finger protein 10 2.3759
MYO1E myosin IE 2.37316
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 2.37206
IVL involucrin 2.37035
MYH9 myosin, heavy chain 9, non-muscle 2.37009
FOXO4 forkhead box O4 2.36763
DERL2 derlin 2 2.36752
YTHDC1 YTH domain containing 1 2.36729
GADD45A growth arrest and DNA-damage-inducible, alpha 2.36659
SETD1B SET domain containing 1B 2.36576
MPRIP myosin phosphatase Rho interacting protein 2.36138
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 2.36026
SYT17 synaptotagmin XVII 2.35411
METTL22 methyltransferase like 22 2.34967
SETD5 SET domain containing 5 2.34819
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 2.34807
SPEG SPEG complex locus 2.34291
CDC34 cell division cycle 34 2.34205
KLF4 Kruppel-like factor 4 (gut) 2.34053
IER2 immediate early response 2 2.33852
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 2.33579
MUC13 mucin 13, cell surface associated 2.33518
SPINK1 serine peptidase inhibitor, Kazal type 1 2.33341
SLC39A2 solute carrier family 39 (zinc transporter), member 2 2.3323
CLASP1 cytoplasmic linker associated protein 1 2.32832
GPRIN2 G protein regulated inducer of neurite outgrowth 2 2.32611
TSG101 tumor susceptibility 101 2.32594
TRIM62 tripartite motif containing 62 2.32021
RNF187 ring finger protein 187 2.31904
CDIP1 cell death-inducing p53 target 1 2.3133
PLA2G15 phospholipase A2, group XV 2.31286
CLIC4 chloride intracellular channel 4 2.31216
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 2.30998
FBXL12 F-box and leucine-rich repeat protein 12 2.3071
MOSPD1 motile sperm domain containing 1 2.30478
ACTMAP actin maturation protease 2.30241
PXDC1 PX domain containing 1 2.30158
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 2.29989
ZNF672 zinc finger protein 672 2.2986
RND1 Rho family GTPase 1 2.2937
IRF9 interferon regulatory factor 9 2.29292
IRF7 interferon regulatory factor 7 2.29286
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.29281
BRD2 bromodomain containing 2 2.28691
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 2.28478
OSBPL2 oxysterol binding protein-like 2 2.28387
SEC16A SEC16 homolog A (S. cerevisiae) 2.27992
ALOXE3 arachidonate lipoxygenase 3 2.27974
TMEM39A transmembrane protein 39A 2.27673
CBX4 chromobox homolog 4 2.27587
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.27385
APLNR apelin receptor 2.27235
C6ORF89 chromosome 6 open reading frame 89 2.2717
ATG2A autophagy related 2A 2.27065
KRT33B keratin 33B, type I 2.2679
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 2.26732
JOSD1 Josephin domain containing 1 2.26267
CHMP1A charged multivesicular body protein 1A 2.261
ERBB3 erb-b2 receptor tyrosine kinase 3 2.25903
FAM53C family with sequence similarity 53, member C 2.25892
TPBG trophoblast glycoprotein 2.2475
CYB5R2 cytochrome b5 reductase 2 2.2403
KRT6A keratin 6A, type II 2.23913
NIBAN1 niban apoptosis regulator 1 2.23681
WDTC1 WD and tetratricopeptide repeats 1 2.22504
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 2.22281
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.21965
MAP2K3 mitogen-activated protein kinase kinase 3 2.21817
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 2.21774
EFS embryonal Fyn-associated substrate 2.21459
PADI2 peptidyl arginine deiminase, type II 2.20647
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 2.20641
IFI27 interferon, alpha-inducible protein 27 2.20311
RHOF ras homolog family member F (in filopodia) 2.2018
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 2.19815
BEST1 bestrophin 1 2.19634
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.19411
ULK2 unc-51 like autophagy activating kinase 2 2.19013
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.18875
KIF21B kinesin family member 21B 2.18593
METTL25B methyltransferase like 25B 2.18588
YIPF1 Yip1 domain family, member 1 2.18483
PODNL1 podocan-like 1 2.18316
CACFD1 calcium channel flower domain containing 1 2.18174
IL17RA interleukin 17 receptor A 2.1816
KIAA1614 KIAA1614 2.17762
PRSS22 protease, serine, 22 2.17487
GABARAP GABA(A) receptor-associated protein 2.17052
ZCCHC24 zinc finger, CCHC domain containing 24 2.17044
RNF39 ring finger protein 39 2.16999
PALLD palladin, cytoskeletal associated protein 2.1679
GRB10 growth factor receptor-bound protein 10 2.16708
BCL2L2 BCL2-like 2 2.16306
SPRR3 small proline-rich protein 3 2.16072
ADAR adenosine deaminase, RNA-specific 2.16046
MACF1 microtubule-actin crosslinking factor 1 2.15788
KCTD15 potassium channel tetramerization domain containing 15 2.15624
PRSS53 protease, serine, 53 2.15263
HAL histidine ammonia-lyase 2.15124
TBX21 T-box 21 2.14989
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.14127
MKRN1 makorin ring finger protein 1 2.14125
LAD1 ladinin 1 2.14079
STBD1 starch binding domain 1 2.13783
TAOK1 TAO kinase 1 2.13668
JAKMIP2 janus kinase and microtubule interacting protein 2 2.13614
PARP6 poly (ADP-ribose) polymerase family, member 6 2.13022
ADGRG1 adhesion G protein-coupled receptor G1 2.12966
MED8 mediator complex subunit 8 2.12479
GPR137B G protein-coupled receptor 137B 2.12199
WBP1L WW domain binding protein 1-like 2.12179
LMTK1 lemur tail kinase 1 2.12135
NBEAL2 neurobeachin-like 2 2.1211
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 2.12092
OASL 2'-5'-oligoadenylate synthetase-like 2.11972
XKR8 XK, Kell blood group complex subunit-related family, member 8 2.11726
HLA-G major histocompatibility complex, class I, G 2.11636
CYB5R1 cytochrome b5 reductase 1 2.11555
EIF1 eukaryotic translation initiation factor 1 2.1149
TGIF1 TGFB-induced factor homeobox 1 2.1144
CASZ1 castor zinc finger 1 2.11331
HOXC11 homeobox C11 2.11318
LCE2B late cornified envelope 2B 2.11303
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.11047
PTGDS prostaglandin D2 synthase 21kDa (brain) 2.10693
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 2.10545
CCNP cyclin P 2.10281
SUCO SUN domain containing ossification factor 2.10232
SNX11 sorting nexin 11 2.09925
RAB25 RAB25, member RAS oncogene family 2.09913
KDM5A lysine (K)-specific demethylase 5A 2.09637
RETREG3 reticulophagy regulator family member 3 2.09517
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.09515
KLC3 kinesin light chain 3 2.09311
FICD FIC domain containing 2.09221
PLK3 polo-like kinase 3 2.09138
FAM168B family with sequence similarity 168, member B 2.08988
NCBP3 nuclear cap binding subunit 3 2.08713
CDR2L cerebellar degeneration-related protein 2-like 2.08465
RMC1 regulator of MON1-CCZ1 2.0788
ZCWPW1 zinc finger, CW type with PWWP domain 1 2.07819
TNNT2 troponin T type 2 (cardiac) 2.07723
ATXN2 ataxin 2 2.07174
CALCB calcitonin-related polypeptide beta 2.06826
CCS copper chaperone for superoxide dismutase 2.06544
VAT1 vesicle amine transport 1 2.06219
TOR1B torsin family 1, member B (torsin B) 2.0602
MFGE8 milk fat globule-EGF factor 8 protein 2.05979
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.05802
CCL3L3 chemokine (C-C motif) ligand 3-like 3 2.05754
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 2.05691
STK38 serine/threonine kinase 38 2.05619
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.05576
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.05479
RLF rearranged L-myc fusion 2.05382
ENTREP1 endosomal transmembrane epsin interactor 1 2.05319
FGF1 fibroblast growth factor 1 (acidic) 2.05236
MTMR11 myotubularin related protein 11 2.05145
STX4 syntaxin 4 2.05134
MX1 MX dynamin-like GTPase 1 2.05065
PLAGL2 pleiomorphic adenoma gene-like 2 2.04413
FEM1C fem-1 homolog c (C. elegans) 2.04274
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.04274
DUSP8 dual specificity phosphatase 8 2.04224
MAST2 microtubule associated serine/threonine kinase 2 2.04211
PSG5 pregnancy specific beta-1-glycoprotein 5 2.04162
MAPK13 mitogen-activated protein kinase 13 2.03928
R3HCC1 R3H domain and coiled-coil containing 1 2.03849
HAX1 HCLS1 associated protein X-1 2.03722
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 2.03696
GLTP glycolipid transfer protein 2.0367
EPHA2 EPH receptor A2 2.03589
LY96 lymphocyte antigen 96 2.0344
ZFYVE26 zinc finger, FYVE domain containing 26 2.03257
EFHD1 EF-hand domain family, member D1 2.02884
DDA1 DET1 and DDB1 associated 1 2.02786
YPEL1 yippee-like 1 (Drosophila) 2.02757
ALOX12B arachidonate 12-lipoxygenase, 12R type 2.02685
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.02617
PPP1R17 protein phosphatase 1, regulatory subunit 17 2.02601
GRAMD2B GRAM domain containing 2B 2.02546
MNT MAX network transcriptional repressor 2.02243
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.02237
NCDN neurochondrin 2.02212
CNMD chondromodulin 2.01891
ZNF821 zinc finger protein 821 2.01504
KHNYN KH and NYN domain containing 2.01425
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.01289
PLD2 phospholipase D2 2.01229
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.01125
SORBS3 sorbin and SH3 domain containing 3 2.01027
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.00877
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 2.00855
ATG9A autophagy related 9A 2.00823
TCHH trichohyalin 2.00787
MZB1 marginal zone B and B1 cell-specific protein 2.00756
TGM3 transglutaminase 3 2.00662
SIL1 SIL1 nucleotide exchange factor 2.00464
RABEP2 rabaptin, RAB GTPase binding effector protein 2 2.00401
LAPTM4A lysosomal protein transmembrane 4 alpha 2.00334
REXO2 RNA exonuclease 2 2.00319
R3HDM4 R3H domain containing 4 2.00261

decreased expression

Symbol Name Standardized Value
UBE2C ubiquitin-conjugating enzyme E2C -8.55377
PSRC1 proline/serine-rich coiled-coil 1 -8.3975
CCNB2 cyclin B2 -8.39235
KIF20A kinesin family member 20A -8.34827
S100A4 S100 calcium binding protein A4 -8.34203
CDC20 cell division cycle 20 -7.94193
MSMO1 methylsterol monooxygenase 1 -7.46439
TOP2A topoisomerase (DNA) II alpha 170kDa -6.50677
PLK1 polo-like kinase 1 -5.85055
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.83116
HSPA8 heat shock 70kDa protein 8 -5.65732
NCAPD2 non-SMC condensin I complex, subunit D2 -5.5935
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -5.52702
BZW2 basic leucine zipper and W2 domains 2 -5.51306
TRAP1 TNF receptor-associated protein 1 -5.49022
STMN1 stathmin 1 -5.45487
CCNB1 cyclin B1 -5.3449
INSIG1 insulin induced gene 1 -5.34372
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -5.30369
NUSAP1 nucleolar and spindle associated protein 1 -5.26107
BIRC5 baculoviral IAP repeat containing 5 -5.2432
DSG2 desmoglein 2 -5.16746
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -5.16465
AURKA aurora kinase A -5.10241
CD320 CD320 molecule -5.01821
KIFBP kinesin family binding protein -4.95463
CDK1 cyclin-dependent kinase 1 -4.90506
SH3D19 SH3 domain containing 19 -4.90044
CCNA2 cyclin A2 -4.81761
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -4.72564
SMNDC1 survival motor neuron domain containing 1 -4.61308
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -4.53127
OIP5 Opa interacting protein 5 -4.4983
HMMR hyaluronan-mediated motility receptor (RHAMM) -4.4614
CDCA3 cell division cycle associated 3 -4.4501
KIF14 kinesin family member 14 -4.44842
PARP1 poly (ADP-ribose) polymerase 1 -4.43504
PGM1 phosphoglucomutase 1 -4.43445
KIF18A kinesin family member 18A -4.34729
NT5DC2 5'-nucleotidase domain containing 2 -4.34393
CYCS cytochrome c, somatic -4.34078
SPC25 SPC25, NDC80 kinetochore complex component -4.32849
PCOLCE2 procollagen C-endopeptidase enhancer 2 -4.32451
ATP5PB ATP synthase peripheral stalk-membrane subunit b -4.28414
CRYZ crystallin, zeta (quinone reductase) -4.2704
NEK2 NIMA-related kinase 2 -4.23752
DNM1L dynamin 1-like -4.21863
LBR lamin B receptor -4.12897
AMDHD2 amidohydrolase domain containing 2 -4.11746
CDC25C cell division cycle 25C -4.08067
CENPA centromere protein A -4.01789
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -3.99119
CDK4 cyclin-dependent kinase 4 -3.94517
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.9443
TTK TTK protein kinase -3.92617
PRCP prolylcarboxypeptidase (angiotensinase C) -3.92081
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.91494
MNAT1 MNAT CDK-activating kinase assembly factor 1 -3.91478
DEPDC1 DEP domain containing 1 -3.90516
CISD1 CDGSH iron sulfur domain 1 -3.89542
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -3.8896
PCNA proliferating cell nuclear antigen -3.8886
HDAC2 histone deacetylase 2 -3.86705
ZSCAN5A zinc finger and SCAN domain containing 5A -3.82744
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -3.7925
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.77251
ALDOC aldolase C, fructose-bisphosphate -3.76445
MRPL3 mitochondrial ribosomal protein L3 -3.69176
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -3.68857
NCAPD3 non-SMC condensin II complex, subunit D3 -3.68268
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.67929
SDHAF3 succinate dehydrogenase complex assembly factor 3 -3.66678
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.62216
CENPI centromere protein I -3.6187
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -3.60136
ADD3 adducin 3 (gamma) -3.59893
CETN3 centrin, EF-hand protein, 3 -3.58172
CDKN3 cyclin-dependent kinase inhibitor 3 -3.57874
ANAPC1 anaphase promoting complex subunit 1 -3.54623
NUP93 nucleoporin 93kDa -3.54076
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -3.5386
FKBP5 FK506 binding protein 5 -3.51207
TSEN2 TSEN2 tRNA splicing endonuclease subunit -3.49585
TCTN3 tectonic family member 3 -3.48766
ELOVL6 ELOVL fatty acid elongase 6 -3.47374
EPHB2 EPH receptor B2 -3.46821
CBX3 chromobox homolog 3 -3.46808
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -3.44756
KIF11 kinesin family member 11 -3.42928
NTHL1 nth endonuclease III-like 1 (E. coli) -3.42282
PBK PDZ binding kinase -3.4224
NUP37 nucleoporin 37kDa -3.41605
PARPBP PARP1 binding protein -3.40949
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -3.39462
NSDHL NAD(P) dependent steroid dehydrogenase-like -3.3938
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.38394
WDR12 WD repeat domain 12 -3.36824
ARHGAP11A Rho GTPase activating protein 11A -3.36693
MYC v-myc avian myelocytomatosis viral oncogene homolog -3.35246
SOAT2 sterol O-acyltransferase 2 -3.34797
ELP4 elongator acetyltransferase complex subunit 4 -3.34682
H2BC12 H2B clustered histone 12 -3.32923
GTF2A2 general transcription factor IIA, 2, 12kDa -3.32702
DBF4 DBF4 zinc finger -3.31926
KIF4A kinesin family member 4A -3.31746
RPA3 replication protein A3, 14kDa -3.31597
ANAPC15 anaphase promoting complex subunit 15 -3.28196
SNRPA small nuclear ribonucleoprotein polypeptide A -3.28176
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -3.27669
RSU1 Ras suppressor protein 1 -3.25836
ZNF274 zinc finger protein 274 -3.24805
KIAA0586 KIAA0586 -3.24023
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.23546
GPD1L glycerol-3-phosphate dehydrogenase 1-like -3.23349
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -3.23179
SCARB1 scavenger receptor class B, member 1 -3.23098
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.22985
ERCC6L excision repair cross-complementation group 6-like -3.22653
ATP5PO ATP synthase peripheral stalk subunit OSCP -3.22523
PROS1 protein S (alpha) -3.22326
HSPA1A heat shock 70kDa protein 1A -3.2095
CCNF cyclin F -3.20778
HOXA5 homeobox A5 -3.19082
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -3.19082
SMYD2 SET and MYND domain containing 2 -3.17697
PIMREG PICALM interacting mitotic regulator -3.17522
RACGAP1 Rac GTPase activating protein 1 -3.17337
MDH1 malate dehydrogenase 1, NAD (soluble) -3.17332
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -3.16695
KIF23 kinesin family member 23 -3.16402
HMGB2 high mobility group box 2 -3.1601
APOO apolipoprotein O -3.15249
BORA bora, aurora kinase A activator -3.14689
MED21 mediator complex subunit 21 -3.14421
CETN2 centrin, EF-hand protein, 2 -3.14387
MRPL12 mitochondrial ribosomal protein L12 -3.14263
MSH2 mutS homolog 2 -3.14202
CEP55 centrosomal protein 55kDa -3.13836
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -3.13643
GPHN gephyrin -3.12099
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -3.11998
COQ3 coenzyme Q3 methyltransferase -3.1194
HSPD1 heat shock 60kDa protein 1 (chaperonin) -3.11213
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -3.09457
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -3.0913
TPX2 TPX2, microtubule-associated -3.0882
SMIM8 small integral membrane protein 8 -3.07524
MEMO1 mediator of cell motility 1 -3.06539
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -3.0605
DPYD dihydropyrimidine dehydrogenase -3.04991
C1GALT1C1 C1GALT1-specific chaperone 1 -3.03956
TRIP13 thyroid hormone receptor interactor 13 -3.03185
APIP APAF1 interacting protein -3.03129
TSPAN6 tetraspanin 6 -3.0284
ERAP2 endoplasmic reticulum aminopeptidase 2 -3.01369
PAK1IP1 PAK1 interacting protein 1 -3.00325
GEMIN2 gem (nuclear organelle) associated protein 2 -2.99892
CENPF centromere protein F, 350/400kDa -2.99245
PEX3 peroxisomal biogenesis factor 3 -2.99225
TUBGCP4 tubulin, gamma complex associated protein 4 -2.98562
PPA1 pyrophosphatase (inorganic) 1 -2.98524
BLMH bleomycin hydrolase -2.97228
FAM200C family with sequence similarity 200 member C -2.9701
INTS13 integrator complex subunit 13 -2.96338
TUBA1B tubulin, alpha 1b -2.95189
NDC80 NDC80 kinetochore complex component -2.94532
VAV3 vav 3 guanine nucleotide exchange factor -2.94401
C1QBP complement component 1, q subcomponent binding protein -2.93648
HMGN2 high mobility group nucleosomal binding domain 2 -2.93438
RPIA ribose 5-phosphate isomerase A -2.92385
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.92073
CPNE3 copine III -2.91853
ATG5 autophagy related 5 -2.91331
TSC22D3 TSC22 domain family, member 3 -2.91227
PHB2 prohibitin 2 -2.89782
ZDHHC6 zinc finger, DHHC-type containing 6 -2.89735
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.89101
RESF1 retroelement silencing factor 1 -2.89002
EBNA1BP2 EBNA1 binding protein 2 -2.88901
GFUS GDP-L-fucose synthase -2.88699
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.8834
EID1 EP300 interacting inhibitor of differentiation 1 -2.8812
CENPE centromere protein E, 312kDa -2.87859
HSPE1 heat shock 10kDa protein 1 -2.87721
SINHCAF SIN3-HDAC complex associated factor -2.87582
PCDHB11 protocadherin beta 11 -2.8592
DERA deoxyribose-phosphate aldolase (putative) -2.85647
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.85415
MTREX Mtr4 exosome RNA helicase -2.85218
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -2.84937
PTTG1 pituitary tumor-transforming 1 -2.8376
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.82105
VPS26C VPS26 endosomal protein sorting factor C -2.81873
LAMC1 laminin, gamma 1 (formerly LAMB2) -2.81097
DNM1 dynamin 1 -2.80838
ECT2 epithelial cell transforming 2 -2.8012
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -2.79673
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.79663
OXCT1 3-oxoacid CoA transferase 1 -2.79357
ATAD2 ATPase family, AAA domain containing 2 -2.79232
SMC4 structural maintenance of chromosomes 4 -2.79231
MCM3 minichromosome maintenance complex component 3 -2.78751
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.78049
SESN1 sestrin 1 -2.77798
GMNN geminin, DNA replication inhibitor -2.77398
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.76755
NIPSNAP2 nipsnap homolog 2 -2.7663
HMGN4 high mobility group nucleosomal binding domain 4 -2.76612
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.76564
CCNG1 cyclin G1 -2.7614
FBL fibrillarin -2.76
SYNJ2BP synaptojanin 2 binding protein -2.73724
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.73601
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -2.73229
PDCD2 programmed cell death 2 -2.73138
ACSL3 acyl-CoA synthetase long-chain family member 3 -2.72604
TACC3 transforming, acidic coiled-coil containing protein 3 -2.72124
PRC1 protein regulator of cytokinesis 1 -2.71917
APEH acylaminoacyl-peptide hydrolase -2.71891
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.7117
PECR peroxisomal trans-2-enoyl-CoA reductase -2.71103
ATP5F1C ATP synthase F1 subunit gamma -2.71101
ANO10 anoctamin 10 -2.70774
ARHGAP15 Rho GTPase activating protein 15 -2.70409
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.70315
H2BC9 H2B clustered histone 9 -2.69994
SRSF2 serine/arginine-rich splicing factor 2 -2.6945
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.69035
PYDC1 PYD (pyrin domain) containing 1 -2.68231
SPDL1 spindle apparatus coiled-coil protein 1 -2.67647
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.67281
UROS uroporphyrinogen III synthase -2.66896
COMMD10 COMM domain containing 10 -2.66559
MAT2B methionine adenosyltransferase II, beta -2.6605
COL4A1 collagen, type IV, alpha 1 -2.655
NUP160 nucleoporin 160kDa -2.63311
CENPN centromere protein N -2.63004
NTAQ1 N-terminal glutamine amidase 1 -2.62975
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.62948
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.62822
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.62682
BLVRA biliverdin reductase A -2.6216
MOCS2 molybdenum cofactor synthesis 2 -2.62091
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -2.62038
SOCS5 suppressor of cytokine signaling 5 -2.62033
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.61742
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.61545
DLAT dihydrolipoamide S-acetyltransferase -2.61209
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.60674
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.59994
PPARG peroxisome proliferator-activated receptor gamma -2.59948
RBMX RNA binding motif protein, X-linked -2.59693
PGAM4 phosphoglycerate mutase family member 4 -2.59463
RBBP9 retinoblastoma binding protein 9 -2.5914
YEATS4 YEATS domain containing 4 -2.58359
MATR3 matrin 3 -2.58272
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.582
SMYD3 SET and MYND domain containing 3 -2.58014
SLC38A6 solute carrier family 38, member 6 -2.56351
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.56331
CS citrate synthase -2.56127
NUBPL nucleotide binding protein-like -2.55558
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.55276
KIF15 kinesin family member 15 -2.55234
NUBP2 nucleotide binding protein 2 -2.55015
NDC1 NDC1 transmembrane nucleoporin -2.5465
SKIC8 SKI8 subunit of superkiller complex -2.54449
NDRG3 NDRG family member 3 -2.53978
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.5374
NOP16 NOP16 nucleolar protein -2.5331
WDR77 WD repeat domain 77 -2.53285
ENC1 ectodermal-neural cortex 1 (with BTB domain) -2.53217
FMNL3 formin-like 3 -2.53145
EIF4E eukaryotic translation initiation factor 4E -2.52639
TUBGCP5 tubulin, gamma complex associated protein 5 -2.52313
SNRPE small nuclear ribonucleoprotein polypeptide E -2.52115
NHP2 NHP2 ribonucleoprotein -2.51752
MBNL1 muscleblind-like splicing regulator 1 -2.51668
CKAP2 cytoskeleton associated protein 2 -2.51639
FXN frataxin -2.51432
CLNS1A chloride channel, nucleotide-sensitive, 1A -2.51195
TCF21 transcription factor 21 -2.50833
HJURP Holliday junction recognition protein -2.50015
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -2.49857
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) -2.49836
UGP2 UDP-glucose pyrophosphorylase 2 -2.49735
BTBD1 BTB (POZ) domain containing 1 -2.49545
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.49064
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.48864
ABHD10 abhydrolase domain containing 10 -2.48222
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.47943
DCAF6 DDB1 and CUL4 associated factor 6 -2.47914
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.47222
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.47027
SYPL1 synaptophysin-like 1 -2.46698
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.46626
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.46585
RAI1 retinoic acid induced 1 -2.46
MKI67 marker of proliferation Ki-67 -2.45992
ZMYM1 zinc finger, MYM-type 1 -2.45924
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -2.45836
AP2M1 adaptor-related protein complex 2, mu 1 subunit -2.45512
MTCH2 mitochondrial carrier 2 -2.45185
BACE2 beta-site APP-cleaving enzyme 2 -2.44983
UTRN utrophin -2.44867
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.43742
MIS18A MIS18 kinetochore protein A -2.43577
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.43427
TMX1 thioredoxin-related transmembrane protein 1 -2.43076
MRPL11 mitochondrial ribosomal protein L11 -2.42937
WDR3 WD repeat domain 3 -2.42455
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -2.42448
LPAR6 lysophosphatidic acid receptor 6 -2.42231
ADSL adenylosuccinate lyase -2.42097
FBXO5 F-box protein 5 -2.41838
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -2.41801
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.4163
TMSB10 thymosin beta 10 -2.41504
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.40949
ZNF322 zinc finger protein 322 -2.40839
PLS1 plastin 1 -2.40791
SSBP2 single-stranded DNA binding protein 2 -2.40083
TRMT5 tRNA methyltransferase 5 -2.39716
RUVBL1 RuvB-like AAA ATPase 1 -2.39395
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.39176
RFC3 replication factor C (activator 1) 3, 38kDa -2.39017
DDIT4 DNA-damage-inducible transcript 4 -2.38584
BRIX1 BRX1, biogenesis of ribosomes -2.38516
EXOSC5 exosome component 5 -2.38111
CAND1 cullin-associated and neddylation-dissociated 1 -2.37773
GRID1 glutamate receptor, ionotropic, delta 1 -2.3745
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.37343
HOXA4 homeobox A4 -2.37308
PUS7 pseudouridylate synthase 7 (putative) -2.37143
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.37108
POGLUT2 protein O-glucosyltransferase 2 -2.36774
PYCR3 pyrroline-5-carboxylate reductase 3 -2.36677
ACP6 acid phosphatase 6, lysophosphatidic -2.36315
MYCBP MYC binding protein -2.36275
PXMP4 peroxisomal membrane protein 4, 24kDa -2.36266
TSFM Ts translation elongation factor, mitochondrial -2.36069
PEX2 peroxisomal biogenesis factor 2 -2.35166
AURKB aurora kinase B -2.35134
MCM10 minichromosome maintenance complex component 10 -2.3511
CACYBP calcyclin binding protein -2.34945
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.34892
KIF20B kinesin family member 20B -2.34778
JPT2 Jupiter microtubule associated homolog 2 -2.34707
THYN1 thymocyte nuclear protein 1 -2.34447
RSRP1 arginine/serine-rich protein 1 -2.34422
HADH hydroxyacyl-CoA dehydrogenase -2.34363
ATXN7L1 ataxin 7-like 1 -2.34138
FASTKD3 FAST kinase domains 3 -2.3405
IL13RA1 interleukin 13 receptor, alpha 1 -2.33946
ZNF557 zinc finger protein 557 -2.33912
PHTF2 putative homeodomain transcription factor 2 -2.32983
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 -2.32959
DHRS3 dehydrogenase/reductase (SDR family) member 3 -2.32539
TMEM50B transmembrane protein 50B -2.32328
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.32247
QARS1 glutaminyl-tRNA synthetase 1 -2.32221
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -2.31826
MRPL16 mitochondrial ribosomal protein L16 -2.31749
FKBP3 FK506 binding protein 3, 25kDa -2.31564
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.31507
NUP205 nucleoporin 205kDa -2.31372
DHFR dihydrofolate reductase -2.3135
VRK1 vaccinia related kinase 1 -2.30532
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.30528
ATP5F1B ATP synthase F1 subunit beta -2.3039
GRWD1 glutamate-rich WD repeat containing 1 -2.30374
RPS5 ribosomal protein S5 -2.3035
APRT adenine phosphoribosyltransferase -2.30264
TK1 thymidine kinase 1, soluble -2.29594
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -2.29372
PRRX1 paired related homeobox 1 -2.2933
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.28687
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -2.2851
MRPL39 mitochondrial ribosomal protein L39 -2.28501
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase -2.28449
NASP nuclear autoantigenic sperm protein (histone-binding) -2.28304
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.2826
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -2.28043
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -2.27841
PRPF31 pre-mRNA processing factor 31 -2.27669
ANXA2 annexin A2 -2.27604
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.27482
NCAPH non-SMC condensin I complex, subunit H -2.27429
VBP1 von Hippel-Lindau binding protein 1 -2.27254
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.2679
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) -2.26645
MPHOSPH9 M-phase phosphoprotein 9 -2.26309
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -2.25849
CALM3 calmodulin 3 (phosphorylase kinase, delta) -2.25799
TFB1M transcription factor B1, mitochondrial -2.25665
GIN1 gypsy retrotransposon integrase 1 -2.25638
NUP43 nucleoporin 43kDa -2.25521
BID BH3 interacting domain death agonist -2.25466
RPP30 ribonuclease P/MRP 30kDa subunit -2.25358
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -2.25204
MTFR1 mitochondrial fission regulator 1 -2.24994
DCK deoxycytidine kinase -2.2496
PDHB pyruvate dehydrogenase (lipoamide) beta -2.24759
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -2.24214
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.23935
MSMB microseminoprotein, beta- -2.23851
PEX11A peroxisomal biogenesis factor 11 alpha -2.23506
PPA2 pyrophosphatase (inorganic) 2 -2.23448
TMEM14A transmembrane protein 14A -2.23213
HMGB1 high mobility group box 1 -2.23161
MANEA mannosidase, endo-alpha -2.23004
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -2.22882
ACLY ATP citrate lyase -2.22351
GLUL glutamate-ammonia ligase -2.22338
RNF130 ring finger protein 130 -2.22235
TUBA1C tubulin, alpha 1c -2.22015
ANKRD49 ankyrin repeat domain 49 -2.21931
CCNH cyclin H -2.21914
F2R coagulation factor II (thrombin) receptor -2.21578
TMEM243 transmembrane protein 243, mitochondrial -2.21202
HNRNPR heterogeneous nuclear ribonucleoprotein R -2.21142
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -2.20768
CCT2 chaperonin containing TCP1, subunit 2 (beta) -2.20759
TRIM28 tripartite motif containing 28 -2.20658
MPC2 mitochondrial pyruvate carrier 2 -2.20627
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -2.20539
SAMHD1 SAM domain and HD domain 1 -2.20381
MRPL42 mitochondrial ribosomal protein L42 -2.20259
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -2.20181
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -2.20131
UBA7 ubiquitin-like modifier activating enzyme 7 -2.20002
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -2.2
OXA1L oxidase (cytochrome c) assembly 1-like -2.19652
SPON1 spondin 1, extracellular matrix protein -2.19531
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.19358
IPO7 importin 7 -2.19111
GEMIN6 gem (nuclear organelle) associated protein 6 -2.18981
SNX4 sorting nexin 4 -2.18757
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -2.18732
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -2.18713
S100A3 S100 calcium binding protein A3 -2.18392
POLM polymerase (DNA directed), mu -2.18378
TMPO thymopoietin -2.18259
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -2.18007
RFC2 replication factor C (activator 1) 2, 40kDa -2.17899
PIERCE1 piercer of microtubule wall 1 -2.17839
ARL15 ADP-ribosylation factor-like 15 -2.17823
FASN fatty acid synthase -2.17672
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.17351
PGK1 phosphoglycerate kinase 1 -2.17287
EXOC5 exocyst complex component 5 -2.17189
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.17181
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -2.16828
FBXL8 F-box and leucine-rich repeat protein 8 -2.16818
SRBD1 S1 RNA binding domain 1 -2.16678
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.16444
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -2.1607
CAPRIN1 cell cycle associated protein 1 -2.15933
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -2.1567
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -2.15666
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.15628
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.15438
MCM4 minichromosome maintenance complex component 4 -2.15148
CHEK2 checkpoint kinase 2 -2.14812
MRS2 MRS2 magnesium transporter -2.14569
RAD51AP1 RAD51 associated protein 1 -2.14488
ETV1 ets variant 1 -2.14382
SLIRP SRA stem-loop interacting RNA binding protein -2.14372
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -2.14352
SPA17 sperm autoantigenic protein 17 -2.14057
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -2.1398
FOXM1 forkhead box M1 -2.13606
CRIP2 cysteine-rich protein 2 -2.13407
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -2.13326
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.13244
PRUNE1 prune exopolyphosphatase 1 -2.132
NMD3 NMD3 ribosome export adaptor -2.13187
TFAM transcription factor A, mitochondrial -2.13101
RPS21 ribosomal protein S21 -2.12886
EML4 echinoderm microtubule associated protein like 4 -2.12689
RNASE6 ribonuclease, RNase A family, k6 -2.12663
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.12597
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -2.12491
CLEC10A C-type lectin domain family 10, member A -2.12226
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.12225
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -2.11935
RYK receptor-like tyrosine kinase -2.11406
PCYOX1 prenylcysteine oxidase 1 -2.11276
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -2.11269
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -2.11171
MTA2 metastasis associated 1 family, member 2 -2.10618
EIPR1 EARP complex and GARP complex interacting protein 1 -2.10527
TCEAL4 transcription elongation factor A (SII)-like 4 -2.10506
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -2.1041
MLF1 myeloid leukemia factor 1 -2.10159
TBL3 transducin (beta)-like 3 -2.1014
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.10115
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.09987
GPSM2 G-protein signaling modulator 2 -2.09935
RSBN1 round spermatid basic protein 1 -2.09767
MCM6 minichromosome maintenance complex component 6 -2.09735
APOA1 apolipoprotein A-I -2.09515
MRPS7 mitochondrial ribosomal protein S7 -2.09509
PHB1 prohibitin 1 -2.09506
RNGTT RNA guanylyltransferase and 5'-phosphatase -2.09495
COL4A2 collagen, type IV, alpha 2 -2.09431
ACSM3 acyl-CoA synthetase medium-chain family member 3 -2.09406
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -2.09342
SNX3 sorting nexin 3 -2.09268
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.09051
FABP6 fatty acid binding protein 6, ileal -2.0873
IPO8 importin 8 -2.08476
NLRP2B NLR family pyrin domain containing 2B -2.08373
UBE2N ubiquitin-conjugating enzyme E2N -2.07974
CNOT8 CCR4-NOT transcription complex, subunit 8 -2.0776
PRPF4B pre-mRNA processing factor 4B -2.07672
ACP3 acid phosphatase 3 -2.07478
AP1B1 adaptor-related protein complex 1, beta 1 subunit -2.07471
BCAP29 B-cell receptor-associated protein 29 -2.07435
FJX1 four jointed box 1 (Drosophila) -2.07206
MTAP methylthioadenosine phosphorylase -2.07205
PALS2 protein associated with LIN7 2, MAGUK p55 family member -2.07042
TMEM50A transmembrane protein 50A -2.06774
HBE1 hemoglobin, epsilon 1 -2.06693
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.0634
TMT1A thiol methyltransferase 1A -2.05571
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -2.05495
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.05
SRP9 signal recognition particle 9kDa -2.04984
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -2.04946
TXNDC9 thioredoxin domain containing 9 -2.04869
CKS2 CDC28 protein kinase regulatory subunit 2 -2.04864
KDM1A lysine (K)-specific demethylase 1A -2.04678
MPZL1 myelin protein zero-like 1 -2.04628
CDC27 cell division cycle 27 -2.04592
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.04512
TUBGCP2 tubulin, gamma complex associated protein 2 -2.04486
RPE ribulose-5-phosphate-3-epimerase -2.04137
TCEAL1 transcription elongation factor A (SII)-like 1 -2.04062
SPPL2A signal peptide peptidase like 2A -2.03966
EPS8 epidermal growth factor receptor pathway substrate 8 -2.03942
DUSP9 dual specificity phosphatase 9 -2.03899
HAVCR1 hepatitis A virus cellular receptor 1 -2.0377
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -2.03193
GPN3 GPN-loop GTPase 3 -2.0303
HAT1 histone acetyltransferase 1 -2.0282
NFYB nuclear transcription factor Y, beta -2.02816
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.02781
MCTS1 malignant T cell amplified sequence 1 -2.02719
ENO1 enolase 1, (alpha) -2.02051
LPCAT3 lysophosphatidylcholine acyltransferase 3 -2.01974
ATP5F1A ATP synthase F1 subunit alpha -2.01567
SPAG5 sperm associated antigen 5 -2.01354
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -2.01185
TCTN1 tectonic family member 1 -2.01154
EAPP E2F-associated phosphoprotein -2.00924
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -2.00569
CAMK4 calcium/calmodulin-dependent protein kinase IV -2.00316
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.00295
IRF2 interferon regulatory factor 2 -2.0025
SELENOT selenoprotein T -2.002