| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | melphalan 10.88 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:A24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CNRIP1 | cannabinoid receptor interacting protein 1 | 4.87018 |
| AGR2 | anterior gradient 2 | 3.91596 |
| TCEA2 | transcription elongation factor A (SII), 2 | 3.62673 |
| MAP7 | microtubule-associated protein 7 | 3.32291 |
| STXBP1 | syntaxin binding protein 1 | 3.09599 |
| INPP1 | inositol polyphosphate-1-phosphatase | 3.045 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 2.99381 |
| ZNF586 | zinc finger protein 586 | 2.93713 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 2.91317 |
| HSPB1 | heat shock 27kDa protein 1 | 2.91184 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.7173 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.7092 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 2.65978 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.59898 |
| SATB1 | SATB homeobox 1 | 2.57348 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 2.54531 |
| ABHD4 | abhydrolase domain containing 4 | 2.53788 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 2.52246 |
| TSPAN1 | tetraspanin 1 | 2.48969 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 2.48713 |
| ICAM3 | intercellular adhesion molecule 3 | 2.40964 |
| S100A4 | S100 calcium binding protein A4 | 2.30784 |
| STAP2 | signal transducing adaptor family member 2 | 2.22144 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 2.20489 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 2.16687 |
| PYGL | phosphorylase, glycogen, liver | 2.11406 |
| NDUFS1 | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 2.09747 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.07501 |
| CAVIN2 | caveolae associated protein 2 | 2.05303 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.05108 |
| IFITM1 | interferon induced transmembrane protein 1 | 2.03602 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 2.03031 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 2.00721 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -6.56968 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -4.32635 |
| CDC20 | cell division cycle 20 | -4.25775 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -4.21482 |
| PLK1 | polo-like kinase 1 | -4.04362 |
| HMG20B | high mobility group 20B | -3.65133 |
| CCNB2 | cyclin B2 | -3.54873 |
| HSPA8 | heat shock 70kDa protein 8 | -3.54731 |
| KRT14 | keratin 14, type I | -3.44661 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -3.11336 |
| BAG3 | BCL2-associated athanogene 3 | -3.02925 |
| KIF20A | kinesin family member 20A | -2.9207 |
| PRPF4 | pre-mRNA processing factor 4 | -2.89404 |
| MTFR1 | mitochondrial fission regulator 1 | -2.61361 |
| CCNB1 | cyclin B1 | -2.60141 |
| VDAC1 | voltage-dependent anion channel 1 | -2.58579 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.56095 |
| NLRP4 | NLR family, pyrin domain containing 4 | -2.39349 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -2.34426 |
| COTL1 | coactosin-like F-actin binding protein 1 | -2.32305 |
| DEPDC1 | DEP domain containing 1 | -2.28275 |
| THAP11 | THAP domain containing 11 | -2.26462 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | -2.20478 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -2.19273 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -2.16425 |
| NOSIP | nitric oxide synthase interacting protein | -2.14773 |
| AURKB | aurora kinase B | -2.13806 |
| ZNF385D | zinc finger protein 385D | -2.09192 |
| CCNA1 | cyclin A1 | -2.08574 |
| HSPA1A | heat shock 70kDa protein 1A | -2.06514 |
| LBR | lamin B receptor | -2.03487 |
| PTH2R | parathyroid hormone 2 receptor | -2.00905 |
