CRCGN016_MCF10A.TP53.M_24H:B03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 5.2306
CASP2 caspase 2, apoptosis-related cysteine peptidase 4.28961
TOMM34 translocase of outer mitochondrial membrane 34 3.41768
HBA1 hemoglobin, alpha 1 3.332
VGLL4 vestigial-like family member 4 3.07946
RBBP5 retinoblastoma binding protein 5 2.92765
NUTF2 nuclear transport factor 2 2.59576
IFI6 interferon, alpha-inducible protein 6 2.57226
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.43589
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.39819
MTA2 metastasis associated 1 family, member 2 2.27081
COMP cartilage oligomeric matrix protein 2.2656
MOK MOK protein kinase 2.24467
MDM4 MDM4, p53 regulator 2.20517
WDR76 WD repeat domain 76 2.204
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) 2.09524
TBPL1 TBP-like 1 2.04007
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2.03469
ARPC4-TTLL3 ARPC4-TTLL3 readthrough 2.03346
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 2.02546

decreased expression

Symbol Name Standardized Value
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -4.7799
COTL1 coactosin-like F-actin binding protein 1 -4.49719
DSG2 desmoglein 2 -4.24893
PCCB propionyl CoA carboxylase, beta polypeptide -3.06996
CD58 CD58 molecule -2.91742
HMG20B high mobility group 20B -2.77112
DIPK1A divergent protein kinase domain 1A -2.41953
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.35165
FRS2 fibroblast growth factor receptor substrate 2 -2.18102
S100A8 S100 calcium binding protein A8 -2.14681
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.06439
CHMP4B charged multivesicular body protein 4B -2.0501
SNPH syntaphilin -2.0478