CRCGN016_MCF10A.TP53.M_24H:B04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:B04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CNPY3 canopy FGF signaling regulator 3 4.92199
CXCR4 chemokine (C-X-C motif) receptor 4 4.54418
NCK2 NCK adaptor protein 2 4.32612
PPARG peroxisome proliferator-activated receptor gamma 4.22115
STAP2 signal transducing adaptor family member 2 3.47368
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.48454
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.30272
DENND4B DENN/MADD domain containing 4B 2.07284
CDK3 cyclin-dependent kinase 3 2.03697

decreased expression

Symbol Name Standardized Value
TCTA T-cell leukemia translocation altered -4.79266
HMG20B high mobility group 20B -4.37908
TM9SF3 transmembrane 9 superfamily member 3 -4.05517
MT1X metallothionein 1X -3.77635
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -3.62445
GADD45B growth arrest and DNA-damage-inducible, beta -3.3776
HSPA1A heat shock 70kDa protein 1A -2.9304
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.81864
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.64071
MSN moesin -2.46528
KDM3A lysine (K)-specific demethylase 3A -2.39107
CBR1 carbonyl reductase 1 -2.3825
THAP11 THAP domain containing 11 -2.34
CAB39 calcium binding protein 39 -2.22774
ATP5F1E ATP synthase F1 subunit epsilon -2.1928
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -2.18136
RPL11 ribosomal protein L11 -2.09279
RPS5 ribosomal protein S5 -2.0897
RPL36 ribosomal protein L36 -2.05081
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -2.04307
CCNC cyclin C -2.0354